The effect of hydrogen peroxide on the cyclin D expression in fibroblasts

Activation of mitogen-activated protein (MAP) kinase is essential for cyclin D1 expression and provides a link between mitogenic signalling and cell cycle progression. Hydrogen peroxide (H₂ O₂ ) activates MAP kinase; however, it is not known whether this leads to cyclin D expression. Sustained expression of cyclin D1 and D2 was observed when Her14 fibroblasts were incu-bated with 3 mM or higher H₂ O₂ concentrations. Similar results were obtained when cells were incubated in the presence of serum (FCS). However, the sustained expres-complex sion of cyclin D1 and D2 upon H₂ O₂ treatment was not due to the MAP kinase pathway, because MAP kinase kinase inhibitors did not inhibit cyclin D expression. Furthermore, cyclin D1 and D2 levels remained constant even after addition of a protein synthesis inhibitor, indicating that the effect of H₂ O₂ was not due to induction of protein synthesis. These results indicate that H₂ O₂ reversibly inhibits the ubiquitin-proteasome dependent degra-dation of cyclin D1 and D2, probably by transiently in-hibiting ubiquitination and/or the proteasome. Received 12 March 2001; received after revision 5 April 2001; accepted 9 April 2001     

含噪图象恢复方法的研究

提供了两种含噪图象的恢复算法：农点扫描法和模拟退火法。用这些算法对不同信噪比的图象进行恢复的结果表明：当信噪比较高时，采用逐点扫描法是快速，满意的。在低信噪比时，采用模拟退火法将比逐点扫描法得到更好的恢复效果。     

Turbo译码的改进算法及其性能分析

在传统的Turbo译码算法Log—MAP的基础上，提出改进的SW—Log—MAP算法。仿真表明，改进算法的算法复杂度和存储空间比传统的Log—MAP减少了很多，但是性能几乎没有损失。     

Turbo码新译码算法

Ｔｕｒｂｏ码是一种新的纠错编码,具有十分突出的纠错能力。Ｔｕｒｂｏ码编码端由两个或更多个卷积码并行级联构成,译码端则采用了一种基于软判决信息输入／输出的反馈迭代结构。介绍了Ｔｕｒｂｏ码原理以及现有主要的两种Ｔｕｒｂｏ码译码算法－ＭＡＰ和ＳＯＶＡ,推导并提出了两种改进的译码算法：ＡＬ－１和ＡＬ－２。计算机模拟和定性讨论表明,在白高斯噪声信道下,ＡＬ－１和ＡＬ－２算法既可大大减少计算杂度,又保持了良好     

计算机化自适应测验中能力估计新方法

能力估计的极大似然估计方法(MLE)不能处理全0或全1的被试反应模式,若事先设置好能力估计的上下界,则会导致能力估计的有效范围缩小的后果; 而贝叶斯估计方法需要选择先验分布,先验分布的选择必须很慎重.在原有似然函数的基础上,构建2个新的项目,提出了改进的MLE方法(NMLE).NMLE既不需要能力先验分布,也不会缩小能力估计范围,而且可以处理各种反应模式.蒙特卡洛实验结果表明新方法表现良好.     

Region-based classification by combining MS segmentation and MRF for POLSAR images

Speckle effects on classification results can be suppressed to some extent by introducing the contextual information.An unsupervised classification algorithm is proposed for polarimetric synthetic aperture radar(POLSAR) images based on the mean shift(MS) segmentation and Markov random field(MRF).First,polarimetric features are exacted by target decomposition for MS segmentation.An initial classification is executed by using the target decomposition and the agglomerative hierarchical clustering algorithm.Thereafter,a classification step based on MRF is performed by using the mean coherence matrices obtained for each segment.Under the MRF framework,the smoothness term is defined according to the distance between neighboring areas.By using POLSAR images acquired by the German Aerospace Centre and National Aeronautics and Space Administration/Jet Propulsion Laboratory,the experimental results confirm that the proposed method has higher accuracy and better regional connectivity than other classification methods.     

关于Turbo码可实现解码方法的研究

Turbo码解码算法包括SOVA（soft output viterbi algorithm),MAP(max a posterior),以及LOGMAP算法,其中LOGMAP算兼有高性能和低计算复杂度的优点。为了降低解码复杂度,对LOGMAP算法进行了模拟优化;为进一步减少解码时间,在解码过程中引入了滑动窗技术。并对整个Turbo码解码过程进行量化模拟,得出了优化结果。     

磁共振图像的随机场分割方法

基于Gibbs分布的Markov随机场是一个重要的先验模型,能够简单地通过势能形式表示图像像素之间的相互作用,从而把图像的先验知识和图像分割的数学模型相结合,利用Markov随机场方法提出了脑磁共振图像最大后验概率的分割模型,并通过迭代条件方法求解,与传统的K均值算法作比较,证明了算法的有效性。     

基于事务分解的移动通信并行设计方法

针对称动通信系统给出一种基于事务分解的多任务并行处理设计方案，该方案支持对移多处理，可任意加载多份应用进程，充分利用了多处理器平台的处理能力，并可大大提高的可可靠性和维护性，将其应用于实现归属位置寄存器（HLR）移动应用部分时，该方案在有效地保证事务处理完整性的基础上，使用户数据的一致性和完整性得到保证，此外，新的应用接口的增加可通过增加新的事务处理规则来实现，可以容易地扩展系统功能，而不影响多处理模式，该方案提高了HLR的设计容量和系统性能。     

Integrated Joint Source-Channel Symbol-by-Symbol Decoding of Variable-Length Codes Using 3-D MAP Sequence Estimation

Most of multimedia schemes employ variable-length codes （VLCs） like Huffman code as core components in obtaining high compression rates. However VLC methods are very sensitive to channel noise. The goal of this paper is to salvage as many data from the damaged packets as possible for higher audiovisual quality. This paper proposes an integrated joint source-channel decoder （I-JSCD） at a symbol-level using three-dimensional （3-D） trellis representation for first-order Markov sources encoded with VLC source code and convolutional channel code. This method combines source code and channel code state-spaces and bit-lengths to construct a two-dimensional （2-D） state-space, and then develops a 3-D trellis and a maximum a-posterior （MAP） algorithm to estimate the source sequence symbol by symbol. Experiment results demonstrate that our method results in significant improvement in decoding performance, it can salvage at least half of （50%） data in any channel error rate, and can provide additional error resilience to VLC stream like image, audio, video stream over high error rate links.