Protein folds: molecular systematics in three dimensions

Advances in methods of structure determination have led to the accumulation of large amounts of protein structural data. Some 500 distinct protein folds have now been characterized, representing one-third of all globular folds that exist. The range of known structural types and the relatively large fraction of the protein universe that has already been sampled have greatly facilitated the discovery of some unifying principles governing protein structure and evolutionary relationships. These include a highly skewed distribution of topological arrangements of secondary-structure elements that favors a few very common connectivities and a highly skewed distribution in the capacity of folds to accommodate unrelated sequences. These and other observations suggest that the number of folds is far fewer than the number of genes, and that the fold universe is dominated by a small number of giant attractors that accommodate large numbers of unrelated sequences. Thus all basic protein folds will likely be determined in the near future, laying the foundation for a comprehensive understanding of the biochemical and cellular functions of whole organisms.     

顶缸式连续上板结构的简要设计

本文介绍了顶缸式连续上板机构的设计思路与过程,实现了上料装置的无间断运输功能。根据上板的动作要求,采用顶缸式连续上板结构;顶缸式连续上板结构主要实现换车动作,然后还有上板动作、推板动作、对辊带动板流向流水线的动作。此结构中机构的运作都是由控制系统全程控制,从而实现上板自动化。     

芳香异氰酸酯的制备方法

采用 Curtius重排反应合成芳香异氰酸酯 ,污染少 ,产率较高。     

过氧二甲酰重排反应的理论研究

用ＵＨＦ／ＡＭ１方法研究过氧二甲酰热排反应的机理，结果表明，由自由基对路径是热重排所循的最侍戏，其速控步骤的活化能为９０．１４５ｋＪ．ｍｏｌ＾－１。     

中国移动通信服务行业的竞争发展及其战略调整

论述了中国移动通信服务行业竞争发展的现状，分析了该行业双寡头所做的一些战略性调整方案。     

Estimation procedures for structural time series models

A univariate structural time series model based on the traditional decomposition into trend, seasonal and irregular components is defined. A number of methods of computing maximum likelihood estimators are then considered. These include direct maximization of various time domain likelihood function. The asymptotic properties of the estimators are given and a comparison between the various methods in terms of computational efficiency and accuracy is made. The methods are then extended to models with explanatory variables.     

Tix-Nb1-x合金结构及弹性性质的第一性原理研究

本文基于密度泛函理论的第一性原理计算方法详细地计算了高温高压下不同铌含量对Tix-Nb1-x (x=0, 025, 05, 075,1)二元合金的能量和结构的影响。结果表明,零温零压下不同铌含量下的三种稳定的合金组成结构分别为六角密堆结构Nb025Ti075,体心立方结构 Nb05Ti05和体心立方结构Nb075Ti025,所得的稳定的合金结构晶格参数与相关的实验值和理论值符合的很好。这样, 分别计算了在压强60GPa范围内的稳定的合金结构的弹性性质和弹性模量。     

洛阳市电信大楼结构设计与施工

结合工程实际对高层建筑中结构及基础的选型、布置、人工挖孔扩底桩及地下室侧壁的设计和施工提出了一些建议，经工程实践检验是可行的，可供设计时参考。     

分子重排反应中的吕·查德里原理

从平衡角度出发,讨论分子重排历程中电性平衡的变化规律,看吕·查德里原理在分子重排反应中的体现.     

浅析建筑结构CAD课程的教学方法和内容

通过对建筑结构CAD课程的教学方法和内容两个方面的阐述,使人对建筑结构CAD课程有所了解,明白课程的教学目的、了解课程讲授的核心内容以及提出合理化建议。