浅谈低碳经济背景下如何实践低碳生活

阐述了低碳生活提出的背景和低碳生活的概念,分析了大学生率先实践低碳生活的必要性,探讨了大学生如何从＂衣、食、住、行、用＂5个方面实践低碳生活。     

对专业英语课程教学改革的思考

针对专业英语课程教学存在的问题，结合多年教学实践经验，提出了该课程教学改革的一些建议。     

文化路标Cyborg的隐喻式批判

用以cyborg为代表的高科技对于人类社会的影响进行类比隐喻,以说明现代社会里人们出于狭隘的人本主义观念对科学以及由科学产生的高科技的滥用不仅导致了人类自身主体性的异化,也对立了科技理性和人文精神,威胁到人类社会的可持续性发展。     

用矛盾定律分析查新委托技术资料存在的问题

目的:履行查新人的职业道德,规范查新委托人的学术行为;方法:应用矛盾定律评判问题,应用逻辑推理分析问题;结果:分析出查新委托技术资料存在问题的结症;结论:提醒科研人员在填报查新委托技术资料中要实事求是,科学严谨.     

拟熵权模糊评判法在馆员综合素质评价中的应用

将拟熵权模糊评判法应用于图书馆员综合素质评价之中，建立了一个对于量化模糊性评价因素来说相对完善的评价体系，并结合实例利用Matlab编程实现计算机求解，为图书馆的管理与人力资源开发提供更加科学和实用的技术依据。     

五轴数控机床几何误差参数辨识及实例

用三次多项式对数控机床几何误差进行拟合,建立了与数控机床几何误差模型相适应的测量方案,减少了所需辨识参数的数目,提高了测量效率;利用Matlab软件求解dX的表达式中系数矩阵的条件数,验证了测量点选取的合理性;以一台五轴数控加工中心(TTTRR)为例,对一工件进行误差测量,对其误差参数进行辨识,验证了本文的误差参数辨识方法的可行性及测量方案的合理性.     

新医改下对药品价格的一点思考

目的:对药品价格调整中出现的问题进行探讨并提出建议。方法:分析廉价实用药品退市、部分药品"改头换面"高价上市等情况出现的原因。结论:进一步完善药品定价机制;加强医疗机构的公益补偿将有利于在新医改下药品价格回归的稳定、合理。     

二维铜(Ⅱ)配位聚合物{[Cu(1,3-bip)(1,3-bdc)]·H_2O}_n的合成、晶体结构及热稳定性研究

以1,3-bip(1,3-二咪唑丙烷)、1,3-bdc(间苯二甲酸)和Cu(NO3)2·3H2O为原料,在水热条件下合成了二维铜(Ⅱ)配位聚合物{[Cu(1,3-bip)(1,3-bdc)]·H2O}n,并用元素分析、红外光谱、X-射线单晶衍射对配合物进行了表征.测定结果表明,晶体属三斜晶系,P-1空间群,晶胞参数:a=0.910 50(5)nm,b=1.004 65(7)nm,c=1.154 67(6)nm,α=84.924(5)°,β=89.444(4)°,γ=76.505(5)°.标题配合物中每个Cu(Ⅱ)离子作为一个四连接的节点,通过1,3-bdc和1,3-bip桥联连接形成了二维(4,4)网格结构.此外,通过热重分析研究该配合物的热稳定性.     

Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity

A subset of neurons in the brain, known as 'glucose-excited' neurons, depolarize and increase their firing rate in response to increases in extracellular glucose. Similar to insulin secretion by pancreatic beta-cells, glucose excitation of neurons is driven by ATP-mediated closure of ATP-sensitive potassium (K(ATP)) channels. Although beta-cell-like glucose sensing in neurons is well established, its physiological relevance and contribution to disease states such as type 2 diabetes remain unknown. To address these issues, we disrupted glucose sensing in glucose-excited pro-opiomelanocortin (POMC) neurons via transgenic expression of a mutant Kir6.2 subunit (encoded by the Kcnj11 gene) that prevents ATP-mediated closure of K(ATP) channels. Here we show that this genetic manipulation impaired the whole-body response to a systemic glucose load, demonstrating a role for glucose sensing by POMC neurons in the overall physiological control of blood glucose. We also found that glucose sensing by POMC neurons became defective in obese mice on a high-fat diet, suggesting that loss of glucose sensing by neurons has a role in the development of type 2 diabetes. The mechanism for obesity-induced loss of glucose sensing in POMC neurons involves uncoupling protein 2 (UCP2), a mitochondrial protein that impairs glucose-stimulated ATP production. UCP2 negatively regulates glucose sensing in POMC neurons. We found that genetic deletion of Ucp2 prevents obesity-induced loss of glucose sensing, and that acute pharmacological inhibition of UCP2 reverses loss of glucose sensing. We conclude that obesity-induced, UCP2-mediated loss of glucose sensing in glucose-excited neurons might have a pathogenic role in the development of type 2 diabetes.     

水溶液中相转化制备六方相三氧化钼及其电化学嵌锂性质

三氧化钼(MoO3)以三种常见的物相存在:正交相、六方相和单斜相,前者为热力学稳定相,后两者为热力学介稳相.相对于稳定的正交相MoO3,介稳的六方相MoO3较难制备.笔者采用对已商品化的正交相MoO3再次结晶的方法制得了纯六方相MoO3.通过透射电镜(TEM)观察可知产物为均匀的纳米棒.实验结果表明合成的六方相MoO3的首次放电容量比商品化的正交相MoO3高.六方相MoO3有望成为理想的锂离子电池阴极材料.