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161.
牡丹与寒梅:以两种花卉阐释唐宋士人的差异 总被引:3,自引:0,他引:3
杨朝云 《曲靖师范学院学报》2006,25(1):68-72
在中国古代,历来有花卉鸟兽抒情明志的传统。在特定历史时期中,某种自然物象同特定的情感和意义之间建立了相对稳固的关系,经过社会的认同,物象便转化为人的情感符号而失去了自身客观性质的特征而成为时代的一种标志。牡丹与寒梅就是唐宋两代士人给予充分观照的审美对象,前者艳绚丽、神采外放,代表了唐代建功立业、开张扬厉的时代精神;后者瞿瘦淡雅,外枯中膏,可与宋人淡泊收敛,质朴深微的心态相契合。唐人爱牡丹,宋人重寒梅,从两种花卉的分析中,可对唐宋的时代精神加以阐释。 相似文献
162.
163.
Zhu Canyan Wang Yiming Yang Huibao & Liu Jiasheng School of Electronics Information Engineering Soochow Univ. Suzhou P.R.China 《系统工程与电子技术(英文版)》2006,17(4):875-882
1. INTRODUCTION As the development of technologies of digital signal processing and integrated circuits, the structure of wireless communication system has been improved. Many schemes for software defined radio (SDR) systems have been developed since 1995, and they can be divided into five tiers of solutions according to their developing history and their definitions[1]. The five tiers are conventional hardware-implemented scheme; software-controlled radio scheme; SDR, that implements m… 相似文献
164.
Scorpio A Blank TE Day WA Chabot DJ 《Cellular and molecular life sciences : CMLS》2006,63(19-20):2237-2248
Anthrax has been a major cause of death in grazing animals and an occasional cause of death in humans for thousands of years. Since the late 1800s there has been an exceptional international history of anthrax vaccine development. Due to animal vaccinations, the rate of infection has dropped dramatically. Anthrax vaccines have progressed from uncharacterized whole-cell vaccines in 1881, to pXO2-negative spores in the 1930s, to culture filtrates absorbed to aluminum hydroxide in 1970, and likely to recombinant protective antigen in the near future. Each of these refinements has increased safety without significant loss of efficacy. The threat of genetically engineered, antibiotic and vaccine resistant strains of Bacillus anthracis is fueling hypothesis-driven research and global techniques--including genomics, proteomics and transposon site hybridization--to facilitate the discovery of novel vaccine targets. This review highlights historical achievements and new developments in anthrax vaccine research. 相似文献
165.
α—珠蛋白基因的PCR检测 总被引:2,自引:1,他引:1
用多对引物的复合PCR技术,分别扩增α-珠蛋白基因族中α1和α2基因片段;参照β-珠蛋白基因PCR扩增产物量,判断α1和α2基因是否正常,是否为缺失的纯合子或杂合子,对α-地中海贫血症先征者家系基因型进行PCR分型诊断。 相似文献
166.
以机体硒水平,GSH-Px,SOD的活性,相关的抗癌致癌元素的综合效应比值,食管癌死亡率与硒等元素的多元回归分析及MDA的含量等合指标,评价食管癌患者的硒营养状况,结果表明,食管癌患者的营养状况差,表现为:硒水平低、含硒酶GSG-Px以及抗氧自由基的SOD活性差,脂质过氧化加剧;MDA含量高将使核酸,蛋白质含等含氨基活性物质产生交联反应而使细胞失活,食管癌患者硒营养状况差,与癌肿的一定相关关系,是 相似文献
167.
Structure of the detoxification catalyst mercuric ion reductase from Bacillus sp. strain RC607 总被引:10,自引:0,他引:10
Several hundred million tons of toxic mercurials are dispersed in the biosphere. Microbes can detoxify organo-mercurials and mercury salts through sequential action of two enzymes, organomercury lyase and mercuric ion reductase (MerA). The latter, a homodimer with homology to the FAD-dependent disulphide oxidoreductases, catalyses the reaction NADPH + Hg(II)----NADP+ + H+ + Hg(0), one of the very rare enzymic reactions with metal substrates. Human glutathione reductase serves as a reference molecule for FAD-dependent disulphide reductases and between its primary structure and that of MerA from Tn501 (Pseudomonas), Tn21 (Shigella), p1258 (Staphylococcus) and Bacillus, 25-30% of the residues have been conserved. All MerAs have a C-terminal extension about 15 residues long but have very varied N termini. Although the enzyme from Streptomyces lividans has no addition, from Pseudomonas aeruginosa Tn501 and Bacillus sp. strain RC607 it has one and two copies respectively of a domain of 80-85 residues, highly homologous to MerP, the periplasmic component of proteins encoded by the mer operon. These domains can be proteolytically cleaved off without changing the catalytic efficiency. We report here the crystal structure of MerA from the Gram-positive bacterium Bacillus sp. strain RC607. Analysis of its complexes with nicotinamide dinucleotide substrates and the inhibitor Cd(II) reveals how limited structural changes enable an enzyme to accept as substrate what used to be a dangerous inhibitor. Knowledge of the mode of mercury ligation is a prerequisite for understanding this unique detoxification mechanism. 相似文献
168.
169.
公开密钥体制与Euler-Fermat定理通俗证明 总被引:1,自引:0,他引:1
随着计算机的广泛使用,文件加密解密已成为相当频繁的工作.本文叙述了公开密钥体制中的一种方法,并对其使用的数学工具给出一个通俗证明,以使加密解密工作更加方便、有效. 相似文献
170.
MacArthur DG Seto JT Raftery JM Quinlan KG Huttley GA Hook JW Lemckert FA Kee AJ Edwards MR Berman Y Hardeman EC Gunning PW Easteal S Yang N North KN 《Nature genetics》2007,39(10):1261-1265
More than a billion humans worldwide are predicted to be completely deficient in the fast skeletal muscle fiber protein alpha-actinin-3 owing to homozygosity for a premature stop codon polymorphism, R577X, in the ACTN3 gene. The R577X polymorphism is associated with elite athlete status and human muscle performance, suggesting that alpha-actinin-3 deficiency influences the function of fast muscle fibers. Here we show that loss of alpha-actinin-3 expression in a knockout mouse model results in a shift in muscle metabolism toward the more efficient aerobic pathway and an increase in intrinsic endurance performance. In addition, we demonstrate that the genomic region surrounding the 577X null allele shows low levels of genetic variation and recombination in individuals of European and East Asian descent, consistent with strong, recent positive selection. We propose that the 577X allele has been positively selected in some human populations owing to its effect on skeletal muscle metabolism. 相似文献