力触觉增强的虚拟现实工厂系统

现有虚拟现实工厂只能依靠头戴式显示器和手柄进行单向的视、听觉虚拟操作，难以进行双向的沉浸式触觉交互。针对此问题，采用力反馈控制器设计了一种力触觉增强的虚拟现实工厂系统。以Unity3D为基础，采用3DMax对工厂内多类型工具和零部件进行三维视觉建模，并通过反射探针、光照探针等组件进行立体化视觉增强。在此基础上，为虚拟空间物体增加刚体、碰撞体、关节等组件，建立虚拟空间的触觉反馈模型，实现了力反馈控制器与虚拟空间物体的实时触觉交互。实验表明：系统可提供重力、摩擦力、恒力等多种力触觉感知，支持对20余种工具、零部件的触摸、抓取等触感操作，能感受模型、轮廓以及质量等物理属性，实现了虚拟工厂中“视触听”多维立体化的沉浸式操作。     

A Simple Linear Regression Approach to Modeling and Forecasting Mortality Rates

Observing that a sequence of negative logarithms of 1‐year survival probabilities displays a linear relationship with the sequence of corresponding terms with a time lag of a certain number of years, we propose a simple linear regression to model and forecast mortality rates. Our model assuming the linearity between two mortality sequences with a time lag each other does not need to formulate the time trends of mortality rates across ages for mortality prediction. Moreover, the parameters of our model for a given age depend on the mortality rates for that age only. Therefore, whether the span of the study ages with the age included is widened or shortened will not affect the results of mortality fitting and forecasting for that age. In the empirical testing, the regression results using the mortality data for the UK, USA and Japan show a satisfactory goodness of fit, which convinces us of the appropriateness of the linear assumption. Empirical illustrations further show that our model's performances of fitting and forecasting mortality rates are quite satisfactory compared with the existing well‐known mortality models. Copyright © 2015 John Wiley & Sons, Ltd.     

从智慧城市到智慧区域——新的城市与区域发展模式

 信息技术的快速发展不仅推动了中微观层面上智慧城市的发展建设，在宏观概念上更是未来区域协调高效合作的核心驱动力。中国的智慧城市建设已经体现出由点到面、连片发展的态势，智慧区域建设是必然趋势。对国外智慧区域分析表明智慧区域建设的经验是：重视信息通信技术、注重创新、高效合作、人才培养等。建议国内智慧区域建设重视区域的范围多维化、合作效率高效化、教育与创新积极化、市民参与的多元化等。     

单片机原理与应用设计实验教学改革

针对单片机原理与应用设计实验教学存在的问题,提出实验教学改革措施。通过将Proteus仿真电路设计引入实验教学,提高学生嵌入式系统设计能力。通过设计实验课程知识地图、录制"微课"、设计仿真实验平台等教学资源建设,对实验课教学进行有效支撑,提高学生学习兴趣。此外,改革了课程考核方式,通过成绩杠杆实现对学生的多样性引导,激发学生自主学习积极性。经过两年实践证明,上述实验教学改革措施取得了较好效果。     

Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes

Calorie restriction extends lifespan and produces a metabolic profile desirable for treating diseases of ageing such as type 2 diabetes. SIRT1, an NAD+-dependent deacetylase, is a principal modulator of pathways downstream of calorie restriction that produce beneficial effects on glucose homeostasis and insulin sensitivity. Resveratrol, a polyphenolic SIRT1 activator, mimics the anti-ageing effects of calorie restriction in lower organisms and in mice fed a high-fat diet ameliorates insulin resistance, increases mitochondrial content, and prolongs survival. Here we describe the identification and characterization of small molecule activators of SIRT1 that are structurally unrelated to, and 1,000-fold more potent than, resveratrol. These compounds bind to the SIRT1 enzyme-peptide substrate complex at an allosteric site amino-terminal to the catalytic domain and lower the Michaelis constant for acetylated substrates. In diet-induced obese and genetically obese mice, these compounds improve insulin sensitivity, lower plasma glucose, and increase mitochondrial capacity. In Zucker fa/fa rats, hyperinsulinaemic-euglycaemic clamp studies demonstrate that SIRT1 activators improve whole-body glucose homeostasis and insulin sensitivity in adipose tissue, skeletal muscle and liver. Thus, SIRT1 activation is a promising new therapeutic approach for treating diseases of ageing such as type 2 diabetes.     

单臂氮氧自由基-抗磁金属Cd(Ⅱ)配合物的合成、结构和磁性研究

采用吡啶取代的单臂氮氧自由基与抗磁金属Cd(Ⅱ)进行配位,得到了一个新的单核配合物[Cd(1M4Py)3(OCN)2·2H2O](其中IM4Py=2-(4'-吡啶基)-4,4,5,5-四甲基咪唑啉-1-氧基自由基).单晶X-射线衍射结果表明,配合物属四方晶系,I4(1)/a空间群;晶胞参数a=1 443 9(3)nm,...     

一种基于声-地震耦合的室内声波探雷实验系统

为了研究声波探雷机理,设计了一个基于声-地震耦合原理的室内声波探雷实验系统.首先,简述声波探雷技术的基本原理;然后,详细介绍室内声波探雷实验系统的硬件组成及实验方案;最后,用一种反坦克塑料教练地雷进行实验,重点讨论实验系统的可重复性.实验结果显示,在相同实验条件下,测得的3条地表振动曲线基本重合,表明所设计的实验系统的可重复性良好,满足测试要求,可用于实验室条件下声波探雷机理的研究.     

基于GIS空间分析技术的城市路网可靠性评价方法研究

建立了基于GIS空间分析技术的城市路网可靠性评价方法模型,介绍了基于ArcEngine组件的路网空间查找、空间相交、几何网络连通等方法的详细构建过程与实现代码,并分析了最后以广州-佛山都市圈道路网络的可靠性差异.     

低温-秋水仙素诱导甜瓜多倍体研究

以刚展开子叶的甜瓜植株为材料,采用低温-秋水仙素处理,植株全部成活,通过检测气孔-叶绿体的变化情况,选出4株定植于营养箱内,采收全部植株所结果实,保留种子并测量.采收期过后,用嫩芽叶尖为材料,对3株甜瓜进行染色体计数检测,检出1个四倍体.结果表明:低温-秋水仙素处理可以有效降低秋水仙素的毒害作用,提高植株成活率.植株后期,有由四倍体回复到二倍体的现象,说明在植株生长后期倍性稳定性有所改变.     

土地利用类型变化对城市大气边界层特征影响的数值模拟

利用ENVI和IDL,GIS以及上海市航片,将ARW-WRF中尺度模式中的下垫面土地利用类型数据中上海市部分做了修正:对照模式中24种土地类型分类,将原本定义为农作物耕地和草场,草地,灌木丛,以及沙土和淤泥的部分,根据实际情况改为城区和在建城区,扩大了城市的范围,获取城市建筑物高度信息以得到更精确地粗糙度数据,使其与实...