基于对巯基苯硼酸的糖敏感水凝胶的制备

本文通过简单直接混合海藻酸钠、对巯基苯硼酸和Ca Cl2构建水凝胶。通过扫描电子显微镜观察到水凝胶具有明显的大孔多孔结构。溶胀实验证实随着对巯基苯硼酸浓度的增加,水凝胶的稳定性逐渐增强。此外,随着溶液中葡萄糖浓度的增加,凝胶降解速率逐渐加快。该多孔糖敏感水凝胶有望作为药物载体用于糖尿病的治疗。     

突出工程设计能力培养 增强学生社会适应性

结合学校机械专业特色,突出学生工程设计能力的培养,精心构建机械专业工程设计能力培养体系,强化实践教学环节,重点完善实践教学环境、提高实习教学效果、改善课程设计与毕业设计教学质量,全面提升学生的工程设计能力,增强学生的社会适应性。     

基于蜜罐技术的主动式校园网安全模型研究

针对目前校园网安全采取的大多是被动防御技术,本文将蜜罐技术引入现有传统校园网安全体系中,提出一种新型的主动式校园网安全模型,并给出了其主要功能模块的具体实现.分析表明该模型能够在校园网络中检测出未知的攻击,详细收集攻击者的信息,进一步提高校园网络的主动防御性能.     

蔬菜栽培学教学体会与思考

蔬菜栽培学是园艺专业的一门专业骨干课。本文从培养学生的创新精神、提高学生的实践能力出发，就更新教学内容、改进教学方法、加强实践教学等方面谈了几点体会和建议。     

基于相对暴露度的无黏性均匀泥沙起动流速公式

基于白玉川提出的床面均匀无黏性泥沙双向相对暴露度、拖曳力系数、上举力系数与纵向相对暴露度之间的关系分析发现,当颗粒雷诺数较大时(大于15 700),拖曳力系数、上举力系数仅受相对暴露度影响,且幅值变化较小.CD取值在1~1.22,平均值为1.11;CL取值在0.72~0.99,均值0.86.将拖曳力系数和上举力系数引用到泥沙起动流速公式的研究中,推导出基于相对暴露度的散粒体泥沙起动底部作用流速公式及垂线平均流速公式,通过与现有的天然河道、室内水槽试验得到的泥沙起动流速资料及现有的泥沙起动流速公式比较可知,本文公式与实测资料符合良好,较现有的泥沙起动公式计算精度更高.     

基于混合DBN的海上编队通信链路威胁估计

针对海上编队通信链路威胁估计涉及因素多、知识表示与推理存在不确定性等问题,分析了海上编队通信链路威胁要素,依据要素间因果关系建立了通信链路威胁估计的混合动态贝叶斯网络(DBN)模型,提出了混合DBN模型中连续型网络节点变量的学习方法。仿真分析证实了该方法的有效性和可操作性。     

Human CtIP promotes DNA end resection

In the S and G2 phases of the cell cycle, DNA double-strand breaks (DSBs) are processed into single-stranded DNA, triggering ATR-dependent checkpoint signalling and DSB repair by homologous recombination. Previous work has implicated the MRE11 complex in such DSB-processing events. Here, we show that the human CtIP (RBBP8) protein confers resistance to DSB-inducing agents and is recruited to DSBs exclusively in the S and G2 cell-cycle phases. Moreover, we reveal that CtIP is required for DSB resection, and thereby for recruitment of replication protein A (RPA) and the protein kinase ATR to DSBs, and for the ensuing ATR activation. Furthermore, we establish that CtIP physically and functionally interacts with the MRE11 complex, and that both CtIP and MRE11 are required for efficient homologous recombination. Finally, we reveal that CtIP has sequence homology with Sae2, which is involved in MRE11-dependent DSB processing in yeast. These findings establish evolutionarily conserved roles for CtIP-like proteins in controlling DSB resection, checkpoint signalling and homologous recombination.     

Tibetan plateau aridification linked to global cooling at the Eocene-Oligocene transition

Continental aridification and the intensification of the monsoons in Asia are generally attributed to uplift of the Tibetan plateau and to the land-sea redistributions associated with the continental collision of India and Asia, whereas some studies suggest that past changes in Asian environments are mainly governed by global climate. The most dramatic climate event since the onset of the collision of India and Asia is the Eocene-Oligocene transition, an abrupt cooling step associated with the onset of glaciation in Antarctica 34 million years ago. However, the influence of this global event on Asian environments is poorly understood. Here we use magnetostratigraphy and cyclostratigraphy to show that aridification, which is indicated by the disappearance of playa lake deposits in the northeastern Tibetan plateau, occurred precisely at the time of the Eocene-Oligocene transition. Our findings suggest that this global transition is linked to significant aridification and cooling in continental Asia recorded by palaeontological and palaeoenvironmental changes, and thus support the idea that global cooling is associated with the Eocene-Oligocene transition. We show that, with sufficient age control on the sedimentary records, global climate can be distinguished from tectonism and recognized as a major contributor to continental Asian environments.     

芦丁在二茂铁酰胺/纳米金修饰电极上的电催化行为研究

通过纳米金(NG)和二茂铁酰胺(FcAI)之间的Au-N键合作用,制备了二茂铁酰胺/纳米金修饰玻碳电极(FcAI/NG/GCE),并采用电化学方法对修饰电极进行了表征.同时研究了芦丁在修饰电极上的电化学行为,实验表明,该电极对芦丁的电化学氧化具有明显的催化作用.用示差脉冲伏安法(DPV)对芦丁进行了测定,其氧化峰电流与芦丁的浓度在5.0×10-7-1.0×10-4molL-1范围内呈良好的线性关系,线性相关系数为0.9989,检出限(S/N=3)为1.0×10-7molL-1.     

三相PWM整流器的模糊免疫PID控制

根据模糊参数自整定PID控制和免疫调节机理,设计了一种模糊免疫PID控制器,该控制器综合了模糊控制,免疫调节规律与PID控制技术.将其应用于基于电压定向的直接功率控制中,改善传统PID控制器时整流器的工作性能.仿真结果表明,该方法具有高功率因数、低谐波、动态性能好等优点,并对负载扰动具有良好的抑制效果.