良好生产管理规范与全面质量管理及其在生物制品生产管？…

从质量及生物制品质量的概念出发，阐述了良好生产管理规范（ＧＭＰ）管理模式和全面质量管理（ＴＱＣ）模式的基本内容及其在生物制品行业中的应用，认为ＴＱＣ是当今工业企业的现代化管理手段和方法，而ＧＭＰ是针对药品生产行业制定的一整套保证产品质量的基本要求。要想不断提高企业管理素质，改进产品质量，在生物制品企业中进行ＧＭＰ管理的同时，必须实行ＴＱＣ管理，ＴＱＣ所涉及的内容要比ＧＭＰ更广泛、更全面、而ＧＭＰ的     

质量管理层次结构模型

系统论述了基于全面质量管理（ＴＱＭ）理论的质量观,提出‘硬质量’和‘软质量’的概念,并建立了质量管理的层次结构模型。该质量管理模型由６个层次组成,将产品质量控制和质量管理统一起来。针对模型中各层次的主要内容和支撑技术以及各个质量管理层次之间的相互关系进行了讨论分析,并重点针对产品规划过程中的质量控制和质量保证问题,分析研究了质量功能配置（ＱＦＤ）方法和Ｔａｇｕｃｈｉ质量设计方法的基本原理和工程意义。文中提出的质量管理层次结构模型及其支撑技术为企业实施质量管理改进提供了理论和实践指导     

浅析全面质量管理

全面质量管理是20世纪60年代美国通用电气公司质量经理菲根堡姆（A．V．Feigenbaum）提出的一种全新的质量管理理论和方法。菲根堡姆强调执行质量职能是公司全体人员的责任，要对产品质量产生、形成、实现的全过程进行质量管理，并采取多种多样的方法解决质量问题，把企业各部门的研制质量、维持质量与提高质量的活动构成有效的体系。     

浅谈药品生产的质量管理

加强药品生产的质量管理,提高产品质量,是制药企业参与市场竞争的必要条件.本文就如何加强药品生产的质量管理作了论述,说明了药品生产的质量管理,是生产全过程的质量管理,是全员参与、以人为本的质量管理,是药品生产中产品质量不断改进的质量管理.企业只有加强药品生产的质量管理,提高产品质量,以质量开拓市场,以质量巩固市场,才能取得丰厚利润和更大的经济效益.     

浅谈质量管理在平绒生产中的作用

质量管理是企业生产经营活动中为确保生产社会需要和用户满意的产品,所进行的组织、计划、指挥、控制和协调工作,质量管理的最终目的是从企业的各个方面来保证产品质量。产品质量的好坏是关系到企业信誉乃至生死存亡的的大问题。一个企业要在竞争激烈的市场中求生存,求发展,就必须有过得硬的产品、高质量的产品。那么如何使用企业生产出高质量的产品呢?这就要从管理上下功夫,从质量管理上做文章。管理是为生产服务的,它是社会化大生产的产物。我们从质量管理的发展历史来看,企业的质量管理经历了不同的各个历史阶段,越来越更加科学化、规范…     

加强预制行业管理,确保建筑结构安全

我们现行的预制行业属多部门共同管理，建设行政管理部门管理企业资质，工商行政管理部门管理企业营业执照，技术监督局对企业生产条件和产品质量进行抽查监督，建设工程质量监督站作为建设行政管理部门委托的执法部门主要是对进入现场的预制构件质量履行监督职责。而预制构件生产企业的日常生产是否按照国家规范进行则无法控制，而质量监督站对进入现场的预制构件的质量控制仅仅是通过结构性能的抽查检测，技术监督局对预制厂的产品监督也是分阶段进行的，所以对预制行业的管理存在盲点。     

浅谈生物制品企业GMP实施质量

GMP是生物制品生产和质量管理的基本原则，生物制品企业都应把实施质量放在首位，确保生物制品生产万无一失。     

TQ225．23 TQ225．14 0032丁二酸酐的生产及应用（刊）

ＴＱ２２５．２３ＴＱ２２５．１４００３２丁二酸酐的生产及应用（刊）／牛文兴（宝鸡有机化工厂）／／化工商品科技情报──１９９５年，（１），４３～４５丁二酸酐又称琥珀酸酐，是一种精细化工产品。本文介绍了其化学结构特点及主要反应，工业应用，生产工艺、国内生...     

儿茶酚胺在心室颤动发生上的作用及与环核苷酸的关系

用乙醛酸诱发荧光及放射免疫分析法进一步研究，氯仿诱发小鼠心室颤动（ＶＦ）是由于内源性儿茶酚胺（ＣＡ）快速释放和利血平可防止ＶＦ的发生．实验结果表明：快速吸入氯仿引起小鼠心室及肾上腺ＣＡ释放而致颤，因此，单独耗竭心室ＣＡ或摘除肾上腺均不能防止ＶＦ的发生．利血平防颤与它耗竭ＣＡ，提高心室ｃＧＭＰ水平和降低ｃＡＭＰ／ｃＧＭＰ比值有关．提示：ＣＡ参与ＶＦ发生可能与环核苷酸水平有关；利血平耗竭ＣＡ，也影响ｃＧＭＰ水平．     

浅谈建筑施工中的安全生产管理

建筑施工现场安全生产管理是一个系统性、安全性的管理,其管理内容涉及到各个环节。我国现行的安全生产管理体系是政府统一领导,部门依法监管,企业全面负责,群众参与监督,全社会广泛支持的格局,其管理核心是企业全面负责,落实到施工现场就是要建立以项目经理为项目安全生产的第一责任人,下至技术负责人,专职安全员、工长、班组长、生产工人的安全管理网络,就显得尤为重要了。每个人在网络中     

Markedness and its Interpretation in Language Use

Language markedness is a common phenomenon in languages, and is reflected from hearing, vision and sense, i.e. the variation in the three aspects such as phonology, morphology and semantics. This paper focuses on the interpretation of markedness in language use following the three perspectives, i.e. pragmatic interpretation, psychological interpretation and cognitive interpretation, with an aim to define the function of markedness.     

Lower Paleozoic oil relationships within Williston Basin, Canada

The Williston Basin is a significant petroleum province, containing oil production zones that include the Middle Cambrian to Lower Ordovician, Upper Ordovician, Middle Devonian, Upper Devonian and Mississippian and within the Jurassic and Cretaceous. The oils of the Williston Basin exhibit a wide range of geochemical characteristics defined as "oil families", although the geochemical signature of the Cambrian Deadwood Formation and Lower Ordovician Winnipeg reservoired oils does not match any "oil family". Despite their close stratigraphic proximity, it is evident that the oils of the Lower Palaeozoic within the Williston Basin are distinct. This suggests the presence of a new "oil family" within the Williston Basin. Diagnostic geochemical signatures occur in the gasoline range chromatograms, within saturate fraction gas chromatograms and biomarker fingerprints. However, some of the established criteria and cross-plots that are currently used to segregate oils into distinct genetic families within the basin do not always meet with success, particularly when applied to the Lower Palaeozoic oils of the Deadwood and Winnipeg Formation.     

An Analysis of Catherine＇s Character——Wuthering Heights

Wuthering Heights, Emily Bronte＇s only novel, was published in December of 1847 under the pseudonym Ellis Bell. The book did not gain immediate success, but it is now thought one of the finest novels in the English language. Catherine is the key character of this masterpiece, because everybody and everything center on her though she had a short life. We can understand this masterpiece better if we know Catherine well.     

Features of Women's language

Language is a means of verbal communication. People use language to communicate with each other. In the society, no two speakers are exactly alike in the way of speaking. Some differences are due to age, gender, statue and personality. Above all, gender is one of the obvious reasons. The writer of this paper tries to describe the features of women＇s language from these perspectives： pronunciation, intonation, diction, subjects, grammar and discourse. From the discussion of the features of women＇s language, more attention should be paid to language use in social context. What＇s more, the linguistic phenomena in a speaking community can be understood more thoroughly.     

Characterization of Ordovician carbonate reservoirs, southeastern Saskatchewan, Canada

The discovery of the prolific Ordovician Red River reservoirs in 1995 in southeastern Saskatchewan was the catalyst for extensive exploration activity which resulted in the discovery of more than 15 new Red River pools. The best yields of Red River production to date have been from dolomite reservoirs. Understanding the processes of dolomitization is, therefore, crucial for the prediction of the connectivity, spatial distribution and heterogeneity of dolomite reservoirs.The Red River reservoirs in the Midale area consist of 3～4 thin dolomitized zones, with a total thickness of about 20 m, which occur at the top of the Yeoman Formation. Two types of replacement dolomite were recognized in the Red River reservoir: dolomitized burrow infills and dolomitized host matrix. The spatial distribution of dolomite suggests that burrowing organisms played an important role in facilitating the fluid flow in the backfilled sediments. This resulted in penecontemporaneous dolomitization of burrow infills by normal seawater. The dolomite in the host matrix is interpreted as having occurred at shallow burial by evaporitic seawater during precipitation of Lake Almar anhydrite that immediately overlies the Yeoman Formation. However, the low δ18O values of dolomited burrow infills (-5.9‰～ -7.8‰, PDB) and matrix dolomites (-6.6‰～ -8.1‰, avg. -7.4‰ PDB) compared to the estimated values for the late Ordovician marine dolomite could be attributed to modification and alteration of dolomite at higher temperatures during deeper burial, which could also be responsible for its 87Sr/86Sr ratios (0.7084～0.7088) that are higher than suggested for the late Ordovician seawaters (0.7078～0.7080). The trace amounts of saddle dolomite cement in the Red River carbonates are probably related to "cannibalization" of earlier replacement dolomite during the chemical compaction.     

Design and analysis of generic LBS application developing platform

Location based services is promising due to its novel working style and contents.A software platform is proposed to provide application programs of typical location based services and support new applications developing efficiently. The analysis shows that this scheme is easy implemented, low cost and adapt to all kinds of mobile nework system.     

橡胶颗粒沥青混合料低温抗裂性试验研究

以AC-13级配为基础,将橡胶颗粒代替部分集料掺入混合料中,以低温弯曲试验为评价方法对不同橡胶颗粒掺量下沥青混合料的低温抗裂性进行研究,并引入应变能密度值对混合料的低温抗裂性进行综合评价.试验结果表明:橡胶颗粒沥青混合料试件的破坏微应变均超过2 300,满足冬寒区的技术指标;无论是否掺加橡胶颗粒,随着温度的下降,沥青混合料破坏时的最大弯拉强度增大,弯拉应变降低,劲度模量增大;弯曲应变能密度在胶粒掺量为1%左右时具有较大的弯曲应变能密度值,此时橡胶颗粒沥青混合料具有较好的低温抗裂性.     

低渗透非均质砂岩油藏启动压力梯度研究

理论推导与室内实验相结合,建立了低渗透非均质砂岩油藏启动压力梯度确定方法。首先借助油藏流场与电场相似的原理,推导了非均质砂岩油藏启动压力梯度计算公式。其次基于稳定流实验方法,建立了非均质砂岩油藏启动压力梯度测试方法。结果表明:低渗透非均质砂岩油藏的启动压力梯度确定遵循两个等效原则。平面非均质油藏的启动压力梯度等于各级渗透率段的启动压力梯度关于长度的加权平均;纵向非均质油藏的启动压力梯度等于各渗透率层的启动压力梯度关于渗透率与渗流面积乘积的加权平均。研究成果可用于有效指导低渗透非均质砂岩油藏的合理井距确定,促进该类油藏的高效开发。     

Quantitative trait loci （QTLs） for quality traits related to protein and starch in wheat

Quality traits in wheat （Triticum aestirum L.） were studied by quantitative trait locus （QTL） analysis in a recombinant inbred line （RIL） population, a set of 131 lines derived from Chuan 35050 × Shannong 483 cross （ChSh）. Grains from RILs were assayed for 21 quality traits related to protein and starch. A total of 35 putative QTLs for 19 traits with a single QTL explaining 7.99-40.52% of phenotypic variations were detected on 10 chromosomes, 1D, 2A, 2D, 3B, 3D, 5A, 6A, 6B, 6D, and 7B. The additive effects of 30 QTLs were positive, contributed by Chuan 35050, the remaining 5 QTLs were negative with the additive effect contributed by Shannong 483. For protein traits, 15 QTLs were obtained and most of them were located on chromosomes 1 D, 3B and 6D, while 20 QTLs for starch traits were detected and most of them were located on chromosomes 3D, 6B and 7B. Only 7 QTLs for protein and starch traits were co-located in three regions on chromosomes 1D, 2A and 2D. These protein and starch trait QTLs showed a distinct distribution pattern in certain regions and chromosomes. Twenty-two QTLs were clustered in 6 regions of 5 chromosomes. Two QTL clusters for protein traits were located on chromosomes 1D and 3B, respectively, three clusters for starch traits on chromosomes 3D, 6B and 7B, and one cluster including protein and starch traits on chromosome 1D.     

On Tragic Consciousness In The Works By Ernest Hemingway

As an American modern novelist who were famous in the literary world, Hemingway was not a person who always followed the trend but a sharp observer. At the same time, he was a tragedy maestro, he paid great attention on existence, fate and end-result. The dramatis personae's tragedy of his works was an extreme limit by all means tragedy on the meaning of fearless challenge that failed. The beauty of tragedy was not produced on the destruction of life, but now this kind of value was in the impact activity. They performed for the reader about the tragedy on challenging for the limit and the death.