| 目标因子分析－光度法同时直接测定诺氟沙星维生素C氯霉素和甲硝唑配伍体系 |
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| 引用本文： | 潘忠孝,陈玮,孙少颖,张懋森,李培芳,屈建.目标因子分析－光度法同时直接测定诺氟沙星维生素C氯霉素和甲硝唑配伍体系[J].中国科学技术大学学报,1995(1). |
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| 作者姓名： | 潘忠孝 陈玮 孙少颖 张懋森 李培芳 屈建 |
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| 作者单位： | 中国科学技术大学，安徽省立医院 |
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| 摘 要： | 利用目标因子分析－紫外可见分光光度法对新药诺氟沙星注射液与氯霉素、维生素Ｃ、甲硝唑的配伍静滴液体系进行了同时定量分析，所含组分的回收率为９３．０～１０８．１％．结果表明，配伍后各组分的紫外吸收光谱具有良好的加和性．还讨论了波长范围、波长间隔对测定结果的影响，并同人工种经网络法作了比较．
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| 关 键 词： | 目标因子分析，分光光度法，配伍，诺氟沙星，维生素C，氯霉素，甲硝唑 |
Simultaneous Determination of Proloxacin, Chloramphenicol,Metronidazole and Vitamin C in a Compatible System by Using Target Factor Analysis-UV Spectrophotometry |
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| Pan Zhongxiao,Chen Wei,Sun Shaoying,Zhang Maosen.Simultaneous Determination of Proloxacin, Chloramphenicol,Metronidazole and Vitamin C in a Compatible System by Using Target Factor Analysis-UV Spectrophotometry[J].Journal of University of Science and Technology of China,1995(1). |
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| Authors: | Pan Zhongxiao Chen Wei Sun Shaoying Zhang Maosen |
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| Institution: | Pan Zhongxiao;Chen Wei;Sun Shaoying;Zhang Maosen(University of Science and Technology of China)Li Peifang;Qu Jian(Anhui Provincial Hospital) |
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| Abstract: | The UV-Spectra of compatible systems consistins of Proloxacin injection, Metronidazole injection, Vitamin C injection and Chloramphenicol injection are measured. The concentrations of thedrugs in the comestible systems are determined successfully by means of target factor analysis. The results imply that each drug may keep independent and may also keep its own pharmacolosical characteristics in the compatible systems. The effects of the wavelength range and the selected sampling intervalon the results are discussed. Thirty-nine compatibel systems have been analysed satisfactorily. The results obtained are in good agreement with those by ANN method. |
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| Keywords: | target factor analysis Spectrophotometry proloxacin chloramphenicol metronidazole Vitamin C |
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