Circling behavior induced by phencyclidine in mice and its inhibition by naloxone |
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| Authors: | Y Eshel A M Korczyn |
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| Institution: | (1) Department of Physiology and Pharmacology, Sackler School of Medicine, Tel Aviv University, Ramat Aviv, 69978 Tel Aviv, Israel |
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| Abstract: | Summary Phencyclidine (PCP), when given to mice, induces general hyperactivity and rapid circling, similar to that caused by morphine. These effects are partially antagonized by naloxone.Acknowledgment. We are grateful to Professor A. Kalir for the donation of PCP. Correspondence and reprint requests should be addressed to A. M. Korczyn. |
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| Keywords: | Mice circling behavior phencyclidine naloxone hyperactivity |
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