| 蛋白质组学核心技术研究进展 |
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| 引用本文： | 王阳梦,董银卯,何聪芬.蛋白质组学核心技术研究进展[J].北京工商大学学报(自然科学版),2006,24(4):9-14. |
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| 作者姓名： | 王阳梦 董银卯 何聪芬 |
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| 作者单位： | 北京工商大学,北京市植物资源研究开发重点实验室,北京,100037 |
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| 摘 要： | 人类基因组计划的完成标志着生命科学已进入后基因组时代,蛋白质组学的研究被提升到了前所未有的高度.对蛋白质组学研究中的三大核心技术——双向电泳、生物质谱、生物信息学技术的进展及其应用进行了概述,重点介绍了双向电泳技术和生物质谱技术.
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| 关 键 词： | 蛋白质组学 双向电泳技术 生物质谱技术 生物信息学 |
| 文章编号： | 1671-1513（2006）04-0009-06 |
| 收稿时间： | 2005-06-09 |
| 修稿时间： | 2005-06-09 |
REVIEW OF MAIN TECHNIQUES FOR PROTEOMIC RESEARCH |
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| WANG Yang-meng,DONG Yin-mao,HE Cong-fen.REVIEW OF MAIN TECHNIQUES FOR PROTEOMIC RESEARCH[J].Journal of Beijing Technology and Business University:Natural Science Edition,2006,24(4):9-14. |
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| Authors: | WANG Yang-meng DONG Yin-mao HE Cong-fen |
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| Institution: | Beijing Key Lab of Plant Resources Research and Development, Beijing Technology and Business University, Beijing 100037, China |
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| Abstract: | Followed by the footsteps of genomics, there comes the functional genomics era. Proteomics is a promising new tool for functional genomies. It is generally acknowledged that the reseach of proteomics was based much on the development and improvement of techniques and methods. Recently, two-dimensional electrophoresis with immobilized pH gradients combined with protein identification by mass spectrometry and the analysis of databases is currently the main system for proteomic research. This review presents the current improvements in twodimensional electrophoresis, mass spectrometry and bioinformatics |
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| Keywords: | proteomics two-dimensional electrophoresis bio-MS bioinformatics |
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