Ectopic human chorionic gonadotropin in breast carcinoma |
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Authors: | A Castro P Buschbaum M Nadji W Voigt S Tabei A Morales |
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Institution: | (1) Hormone Research Lab., Department of Pathology, University of Miami School of Medicine, 33101 Miami, Florida, USA |
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Abstract: | Summary Immunoreactive human chorionic gonadotropin (hCG) was found in 9 of 65 surgically removed malignant breast tumors. Concentrations ranged from 5 to greater than 500 mIU hCG/g tumor. hCG was measured by a -chain specific radioimmunoassay. In further study of these specimens, an immunoperoxidase staining technique was used to stain for hCG in formalin-fixed sections. The hCG was shown to be localized within the cytoplasm and on the surface of the malignant cells. |
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