Capillary electrophoresis in the presence of fosfomycin

Fosfomycin, a sodium salt ofcis-(3-methyloxiranyl) phosphonic acid, was used as electrolyte in binary methanol-water media for capillary electrophoresis. The variety of electroosmotic flow with pH^*, methanol concentration and ionic strength was investigated. The migration behavior of nine bases was examined under various conditions, and the separation of thymine, cytosine, 5-flurouracil, 4, 6-diamino-pyrimidine, purine was accomplished. Foundation item: Supported by the National Science Foundation of China (29875020) Biography, XIE Min-Jie (1976-), male, Ph. D candidate, Research direction: capillary electrophoresis.