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Natural occurrence of 2-5A in interferon-treated EMC virus-infected L cells. |
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| Authors: | B R Williams R R Golgher R E Brown C S Gilbert I M Kerr |
| Abstract: | Until now the interferon-mediated 2'-5' adenine oligonucleotide inhibitors (2-5A) of cell-free protein synthesis have not been detected in intact cells. Here we report their natural occurrence in interferon-treated, EMC virus-infected mouse L cells in amounts consistent with the idea that they play a part in the inhibition of virus growth. |
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