| 饮食限制58d对小鼠学习记忆及抗氧化能力的影响 |
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| 引用本文： | 邵邻相,李姣,徐玲玲,张均平,来树圆,蔡舒君,叶信哲.饮食限制58d对小鼠学习记忆及抗氧化能力的影响[J].浙江师范大学学报(自然科学版),2011,34(1):81-85. |
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| 作者姓名： | 邵邻相 李姣 徐玲玲 张均平 来树圆 蔡舒君 叶信哲 |
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| 作者单位： | 浙江师范大学,化学与生命科学学院,浙江,金华,321004 |
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| 基金项目： | 浙江省自然科学基金资助项目 |
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| 摘 要： | 采用行为观察和生化检测方法,研究了饮食限制58 d对小鼠学习记忆的影响及其各组织中超氧化物歧化酶(SOD)活性和丙二醛(MDA)含量的变化.结果显示:限食小鼠在新环境中更显得不安,66.7%饮食限制组小鼠记忆能力最弱而空间识别能力最强4,0%饮食限制组小鼠学习能力最强;限食小鼠各器官的脏器系数相比自由饮食组都有所升高;各组小鼠所测器官的SOD活性没有明显的区别,但心、肾和脑中MDA含量随饮食限制水平的升高而增高.提示饮食限制对机体器官有一定的损伤作用,适当饮食限制能提高学习能力,但对抗氧化能力的影响不明显.
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| 关 键 词： | 饮食限制 学习记忆 脏器系数 抗氧化能力 |
The effects of dietary restriction on behavior and physiological biochemical of mice |
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| SHAO Linxiang,LI Jiao,XU Linlin,ZHANG Junping,LAI Shuyuan,CAI Shujun,YE Xinzhe.The effects of dietary restriction on behavior and physiological biochemical of mice[J].Journal of Zhejiang Normal University Natural Sciences,2011,34(1):81-85. |
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| Authors: | SHAO Linxiang LI Jiao XU Linlin ZHANG Junping LAI Shuyuan CAI Shujun YE Xinzhe |
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| Institution: | SHAO Linxiang,LI Jiao,XU Linlin,ZHANG Junping,LAI Shuyuan,CAI Shujun,YE Xinzhe(College of Chemistry and Life Science,Zhejiang Normal University,Jinhua Zhejiang 321004,China) |
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| Abstract: | The effects of dietary restriction on learning-memory of mice,the activity of superoxide dismutase(SOD) and the content of malonaldehyde(MDA) were investigated through behavior observation and biochemistry analysis.Compared with the control group,the results were as follows: the dietary restriction mice were in tranquil in new environment,and 66.7% DR group had the weakest memory,while with the spatial identification strongest.The leaning capacity of 40% DR group was strongest.The organ coefficient increase... |
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| Keywords: | dietary restriction learning and memory organ coefficient antioxidation |
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