性激素对大鼠前列腺腹叶酸性磷酸酶影响的组织化学研究

成年雄性Ｗｉｓｔａｒ大鼠８０只分为５组：即对照组（Ｎ组）、正常用雌激素处理组（Ｎ＋Ｅ２）、阉割组（Ｃ组）、阉割后用雌激素处理组（Ｃ＋Ｅ２组）和阉割后用雄激素处理组（Ｃ＋Ｔ组）。于处理后第１、２、３、６和１２周分５批取材。用酶组化方法显示大鼠前列腺腹叶（ＲＶＰ）酸性磷酸酶（ＡＣＰ）的活性变化。结果表明：Ｎ＋Ｅ２组酶活性明显增强，Ｃ组酶活性逐渐减弱，直到消失，Ｃ＋Ｅ２组和Ｃ组结果相似，仅第２周稍有增加，Ｃ＋Ｔ组酶活性变化不明显，提示ＲＶＰ上皮细胞内ＡＣＰ的活性变化与大鼠体内性激素的含量和平衡状态密切相关。

Enzyme Histochemical Study of the Effect of Sex HormoneOf the Acid Phosphatase in Rat Ventral Prostate

Eighty adult male wistar rats were used and divied into five groups;i.e.normal controlgrup.(N),estradiol treatment (N+E2) castration (C),castration combined with setradiol tratment(C+E2) and castration combined with testosterone (C+T).The prostatic tissues were prepared forHistochemical staining at lth,2th,3th,6th and 12th weeks after treatmented,Enzyme Histochemicalmethod was used to demonstrate acid phosphatase (ACP) in the rat ventral prostate.The results were asfollows'ACP activity was increased in N+E2and C groups was gradually decreased to disappears.The results was similar between C+E2 and C groups and don, change in C+T group.lt is suggested that ACPActivity change in RVP might be involved in content and balancd condition of sex hormone.