The suppression of mouse spontaneous locomotor activity by the ingestion of deuterium oxide |
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Authors: | Carol J. Hayes J. D. Palmer |
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Affiliation: | (1) Department of Biology, St. Joseph College, 11205 Brooklyn, New York, USA;(2) Department of Zoology, University of Massachusetts, 01002 Amherst, Massachusetts, USA |
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Abstract: | Summary The spontaneous locomotor activity of the laboratory mouse is significantly depressed by the ingestion of deuterium oxide. The response, which is reversible, is a rectilinear one with up to 70% reduction in activity with the administration of 25% heavy water. |
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