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| 沙樱桃黄酮对SGC-7901细胞增殖的抑制作用 | |
| 引用本文： | 刘成松,吴学桂,谢明仁,俞发荣. 沙樱桃黄酮对SGC-7901细胞增殖的抑制作用[J]. 甘肃科学学报, 2009, 21(1): 66-68 |
| 作者姓名： | 刘成松 吴学桂 谢明仁 俞发荣 |
| 作者单位： | 1. 甘肃省中医学院,附属医院药剂科,甘肃,兰州,730000 2. 民勤县中医院,门诊科,甘肃,民勤,733300 3. 甘肃政法学院,公安分院实验中心,甘肃,兰州,730070 |
| 基金项目： | 甘肃省科学事业费科研计划 |
| 摘 要： | 给予体外培养SGC-7901细胞沙樱桃黄酮，用克隆形成法和X射线能量色散谱仪，测定对细胞分裂增殖和细胞内微量元素含量的影响．结果表明，沙樱桃黄酮（O．1，0．5，5mg·L^-1）组和5-Fu组克隆数比对照组明显减少，抑制率分别为27．60%44．50％、66．60％和40．80％；细胞内Ca^2＋离子水平随给药浓度的增加而升高，K件和P件离子浓度则降低． |
| 关 键 词： | 沙樱桃黄酮 SGC-7901细胞 细胞增殖 |
Inhibition Effects of Nitraria Tangutorum Flavone on SGC-7901 Cell Proliferation |
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| LIU Cheng-song,WU Xue-gui,XIE Ming-ren,YU Fa-Rong. Inhibition Effects of Nitraria Tangutorum Flavone on SGC-7901 Cell Proliferation[J]. Journal of Gansu Sciences, 2009, 21(1): 66-68 | |
| Authors: | LIU Cheng-song WU Xue-gui XIE Ming-ren YU Fa-Rong |
| Affiliation: | LIU Cheng-song, WU Xue-gui, XIE Ming-ren, YU Fa-Rong(1. Department of Medicament, Hospital of Gansu Provicial Traditional Chinese Medicine College, Lanzhou 730000, China; 2. Department of Outpatient Service, Traditional Chinese Medicine Hospital, Minqin 733300, China 3. Experimental Center of Public Security ,Gansu Institute of Political Science and Law ,Lanzhou 730070 ,China) |
| Abstract: | In vitro cultured SGC-7901 strain cells,the proliferous effects of NTF on SGC-7901 strain cells were determined with the method of clone formation, and the microelements in cells were detected with X-electron microscope scanning. Results showed that the clones in NTF group（0.1,0.5 and 5mg · L^-1） and the 5-FU group were decreased compared to the control group,and the inhibition rate was 27.60%, 44.50%,66.60% and 40.80% , respectively. X-electron microscope showed that Ca^2＋ was increased and K^1＋ and p^3＋ were decreased in the cell with the increase of NTF. |
| Keywords: | nitraria tangutorum flavone（NTF） SGC-7901 strain cells cell proliferation |
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