Ca2+ uptake and distribution in alloxan-diabetic rat arterial and venous smooth muscle |
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| Authors: | P D M V Turlapaty B T Altura B M Altura |
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| Institution: | (1) Downstate Medical Center, Department of Physiology, State University of New York, 450 Clarkson Avenue, Box 31, 11203 Brooklyn, New York, USA |
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| Abstract: | Summary This report demonstrates that in experimental diabetes mellitus (DM) calcium uptake and its distribution is altered in rat aortic but not in portal venous smooth muscle. Results are interpreted as consequences of increased calcium binding by aortic smooth muscle in experimental DM, which could account for the hyporeactivity of alloxan diabetic rat aorta reported previously.Supported by NIH grant No.HL-18015 and NIDA grant No. DA-02339. |
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