Comportamento dell allossanain vivo

Summary The author describes a microprocedure, based on the o-phenylenediamine reaction, for the determination of alloxan in blood and tissuesin vivo. With this method he has been able to determine alloxan in blood, liver, kidney, muscle, and pancreas of rats treated with diabetogenous doses of alloxan. This substance has been found in the blood and tissues during an hour and a half after the injection and in the urine collected directly from the ureter a quarter of an hour after the injection.