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Evaluation for cell affinity of the composite material containing carbon nanotubes
引用本文:KANGShizhao WANYuqing YANHuijuan BEIJianzhong WANGChen WANGShenguo WANGChunru WANLijun BAIChunli. Evaluation for cell affinity of the composite material containing carbon nanotubes[J]. 科学通报(英文版), 2004, 49(20): 2126-2128. DOI: 10.1007/BF03185776
作者姓名:KANGShizhao WANYuqing YANHuijuan BEIJianzhong WANGChen WANGShenguo WANGChunru WANLijun BAIChunli
作者单位:[1]KeyLaboratoryofMolecularNanostructure&Nanotechnology,ChineseAcademyofSciences,Beijing100080.China [2]StateKeyLaboratoryofPolymerPhysics&Chemistry.InstituteofChemistry.ChineseAcademyofSciences.Beijing100080,China
摘    要:The composite material of poly-(L-lactide) (PLLA) and carbon nanotubes (CNTs) were prepared. Its surface morphologies and property were worked out by using atomic force microscopy (AFM) and contact angle measurement. Moreover, the prime cytocompatibility was used to investigate the biocompatibility of the composite material containing CNTs and the effects of CNTs on one aspect of cell function, cell affinity. The results obtained indicate that the composite material of PLLA and CNTs possesses good biocompatibility for both the 3T3 fibroblasts and Oct-1 osteoblast-like cells. The addition of CNTs will greatly affect cell affinity of the material, which may be disadvantage for the cell adhesion.

关 键 词:CNT PLLA AFM
收稿时间:2004-04-30
修稿时间:2004-06-01

Evaluation for cell affinity of the composite material containing carbon nanotubes
KANG Shizhao,WAN Yuqing,YAN Huijuan,BEI Jianzhong,WANG Chen,WANG Shenguo,WANG Chunru,WAN Lijun , BAI Chunli . Key Laboratory of Molecular Nanostructure , Nanotechnology,Chi-nese Academy of Sciences,Beijing ,China, . State Key Laboratory of Polymer Physics , Chemistry. Evaluation for cell affinity of the composite material containing carbon nanotubes[J]. Chinese science bulletin, 2004, 49(20): 2126-2128. DOI: 10.1007/BF03185776
Authors:KANG Shizhao  WAN Yuqing  YAN Huijuan  BEI Jianzhong  WANG Chen  WANG Shenguo  WANG Chunru  WAN Lijun & BAI Chunli . Key Laboratory of Molecular Nanostructure & Nanotechnology  Chi-nese Academy of Sciences  Beijing   China   . State Key Laboratory of Polymer Physics & Chemistry
Affiliation:KANG Shizhao1, WAN Yuqing2, YAN Huijuan1, BEI Jianzhong2, WANG Chen1, WANG Shenguo2, WANG Chunru1, WAN Lijun1 & BAI Chunli1 1. Key Laboratory of Molecular Nanostructure & Nanotechnology, Chi-nese Academy of Sciences, Beijing 100080, China; 2. State Key Laboratory of Polymer Physics & Chemistry, Institute ofChemistry, Chinese Academy of Sciences, Beijing 100080, China
Abstract:The composite material of poly-(L-lactide) (PLLA) and carbon nanotubes (CNTs) were prepared. Itssurface morphologies and property were worked out by us-ing atomic force microscopy (AFM) and contact angle meas-urement. Moreover, the prime cytocompatibility was used to investigate the biocompatibility of the composite materialcontaining CNTs and the effects of CNTs on one aspect of cell function, cell affinity. The results obtained indicate that thecomposite material of PLLA and CNTs possesses good bio-compatibility for both the 3T3 fibroblasts and Oct-1 os-teoblast-like cells. The addition of CNTs will greatly affectcell affinity of the material, which may be disadvantage for the cell adhesion.
Keywords:carbon nanotube   composite material   cell   poly-(L-lac-tide)   biocompatibility.
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