| 基因调节物—c—GMP在小鼠体内的示踪动力学研究 |
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| 引用本文： | 翟永功,马建岗.基因调节物—c—GMP在小鼠体内的示踪动力学研究[J].西北大学学报,1997,27(4):359-362. |
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| 作者姓名： | 翟永功 马建岗 |
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| 作者单位： | 西安交通大学生物工程研究所 |
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| 摘 要： | 通过同位素示踪方法，结合药物动力学原理，对外源性环鸟苷酸（ｃＧＭＰ）作示踪动力学研究，得出了外源性ｃＧＭＰ在小白鼠体内配置状态的量变规律，是具有吸收因素的一室模型。通过对实验数据的计算机处理，获得了一种微机用示踪动力学专用程序（ＭＣＴＫＰ）。
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| 关 键 词： | cGMP 小鼠 示踪动力学 |
Trace Kinetice Study on Gene Moderator 3H cGMP in Mouse in Vivo |
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| Zhai Yonggong,Ma Jiangang,Zhao Wenming.Trace Kinetice Study on Gene Moderator 3H cGMP in Mouse in Vivo[J].Journal of Northwest University(Natural Science Edition),1997,27(4):359-362. |
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| Authors: | Zhai Yonggong Ma Jiangang Zhao Wenming |
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| Abstract: | Istopic trace kinetics was used on this study. Mouse received 3H cGMP through abdominal cavity injection. Blood samples were collected at intervals of different time by cutting tail after injection. Blood sample were treated through chemical digestive mothed, then blood radioactive consistency is determined after treating trace kinetics system. As a result, methematics model of blood radioactive consistency varity vegular patten of 3H cGMP is monocompartment model with profound absorption factor. |
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| Keywords: | tritium labeled cyclic GMP trace kinetics mouse |
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