Morphological aspects of chemically stimulated bovine chromaffin cells

Summary Isolated bovine chromaffin cells were chemically stimulated. The resulting appearance of local changes in membrane structure were compared with the integration of granular proteins into the cell membrane as seen after binding of fluorescence labeled anti-dopamine--hydroxylase. Protuberances of the cell membrane which can be perceived by Nomarski contrast optics are largely congruent with local tracer accumulations at the cell surface.