Differential effects of prostaglandins and isoproterenol on cAMP content and Na, K pump activity in rat submandibular acini |
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| Authors: | J R Martinez N Cassity S Barker |
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| Affiliation: | Department of Child Health, University of Missouri School of Medicine, Columbia 65212. |
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| Abstract: | The beta-adrenergic agonist isoproterenol and prostaglandins E1 and E2 (but not F2 alpha) increased the cAMP content of rat submandibular acini in vitro, but only isoproterenol enhanced ouabain-sensitive 86Rb (K) uptake. These findings suggest that cAMP is not involved in the activation of the Na, K pump in salivary cells. |
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