| Mycotoxin fumonisins: Health impacts and biosynthetic mechanism |
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| 引用本文： | WANG Qiaomei,WANG Jiansheng,YU Fengan,ZHU Xiangcheng,Zaleta-Rivera Kathi,DU Liangcheng. Mycotoxin fumonisins: Health impacts and biosynthetic mechanism[J]. 自然科学进展(英文版), 2006, 16(1): 7-15. DOI: 10.1080/10020070612331343186 |
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| 作者姓名： | WANG Qiaomei WANG Jiansheng YU Fengan ZHU Xiangcheng Zaleta-Rivera Kathi DU Liangcheng |
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| 作者单位： | Department of |
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| 摘 要： | Fumonisins are one of the most important groups of mycotoxins in agriculture and the food industry. They are produced by several widespread fungal pathogens of corn. Fumonisin contamination in maize?derived food and feeds causes several fatal diseases in livestock and poses a significant cancer risk to humans (Group 2B carcinogen). In the recent years, fumonisins have become a hot area in mycotoxin research. This review attempts to highlight the progress in the studies of molecular mechanisms for fumonisin biosynthesis and mode of action. The current understandings in the molecular basis for the cellular effects induced by fumonisins are discussed. Special attentions are paid to introduce the progress in the characterization of individual genes and enzymes involved in the biosynthesis of fumonisins.
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| 关 键 词： | mycotoxins fumonisins biosynthesis food safety |
Mycotoxin fumonisins: Health impacts and biosynthetic mechanism |
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| WANG Qiaomei,WANG Jiansheng,YU Fengan,ZHU Xiangcheng,Zaleta-Rivera Kathia,DU Liangcheng. Mycotoxin fumonisins: Health impacts and biosynthetic mechanism[J]. Progress in Natural Science, 2006, 16(1): 7-15. DOI: 10.1080/10020070612331343186 |
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| Authors: | WANG Qiaomei WANG Jiansheng YU Fengan ZHU Xiangcheng Zaleta-Rivera Kathia DU Liangcheng |
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| Affiliation: | 1. Department of Horticulture, Zhejiang University, The State Agriculture Ministry Laboratory of Horticultural, Plant Growth Development & Biotechnology, Hangzhou 310029, China
2. Department of Chemistry, University of Nebraska, Lincoln, NE 68588-0304,USA |
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| Abstract: | Fumonisins are one of the most important groups of mycotoxins in agriculture and the food industry. They are produced by several widespread fungal pathogens of corn. Fumonisin contamination in maize?derived food and feeds causes several fatal diseases in livestock and poses a significant cancer risk to humans (Group 2B carcinogen). In the recent years, fumonisins have become a hot area in mycotoxin research. This review attempts to highlight the progress in the studies of molecular mechanisms for fumonisin biosynthesis and mode of action. The current understandings in the molecular basis for the cellular effects induced by fumonisins are discussed. Special attentions are paid to introduce the progress in the characterization of individual genes and enzymes involved in the biosynthesis of fumonisins. |
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| Keywords: | mycotoxins fumonisins biosynthesis food safety |
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