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The pharmacological relevance of vital staining with neutral red
Authors:Z Nemes  R Dietz  J B Lüth  S Gomba  E Hackenthal  F Gross
Institution:(1) Present address: Department of Pathology, University Medical School Debrecen, H-4012 Debrecen, Hungary;(2) Department of Pharmacology, University of Heidelberg, Im Neuenheimer Feld 366, D-6900 Heidelberg, (Federal Republic of Germany)
Abstract:Summary The uptake of neutral red into the renin-containing juxtaglomerular granules does not inhibit the release of renin either in basal or in stimulated states of renin secretion. The vasodilating effect of neutral red may be due to a non-specific binding to noradrenaline-receptors in the vascular smooth muscle cells.This work was supported by the German Research Foundation within the SFB 90 lsquoCardiovasculäres Systemrsquo.
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