Annonacin,a novel,biologically active polyketide fromAnnona densicoma |
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| Authors: | T G McCloud D L Smith C -J Chang J M Cassady |
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| Institution: | (1) Department of Medicinal Chemistry and Pharmacognosy, School of Pharmacy and Pharmacal Sciences, Purdue University, 47907 West Lafayette, Indiana, USA |
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| Abstract: | Summary A new linear polyketide, Annonacin (I), has been isolated from active extracts of the stembark ofAnnona densicoma Mart. Annonacin (I) is highly cytotoxic and is active in an assay designed to detect antimitotic agents. The structure of (I) was determined by analysis of spectroscopic data.25 September 1986 |
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| Keywords: | Annonacin polyketide Annona densicoma Annonaceae biological activity |
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