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Molecular cloning of cDNA for murine interleukin-3
Authors:M C Fung  A J Hapel  S Ymer  D R Cohen  R M Johnson  H D Campbell  I G Young
Abstract:The cDNA sequence for murine interleukin-3, one of the colony stimulating factors that regulate haematopoiesis, codes for a polypeptide of 166 amino acids including a putative signal peptide. The predicted amino acid sequence indicates that formation of mature interleukin-3 involves proteolytic removal of not only the signal peptide but additional amino-terminal amino acids.
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