锌布片质量标准葡萄糖酸锌溶出度的测定

锌布片中有效成分葡萄糖酸锌溶出度的测定，是通过对溶出仪转速的控常l，溶媒的选择，方法学的验证（包括最大吸收波长的确定、辅型剂及其它有效成分对测定的影响、精密度试验、回收试验、溶出均一性试验等一系列验证试验），最终证实了本方法科学、合理，完全能够用于锌布片质量标准——葡萄糖酸锌溶出度的测定（锌布片中葡萄糖酸锌溶出度测定的时限为30min，溶出限度为75％）．

The Measuring for Zicold Tablets Quality Standard of Zinc Gluconate Dissolution

The measurement of effective ingredients zinc gluconate dissolution in zicold is through the control for the rotation speed of dissolution instrument, the choice of solvent, the examining of methodology （including the determination of the biggest absorption wave length, the effect of pharmacentieal excipient and other effective ingredients on measurement, accuracy experiment, recovery experiment dissolcation uniformity and so on, a series of proof test）. At last, it proved the method was scientific, reasonable.It can completely apply to the zicold tablets quality standard： the measurement of zinc gluconate dissolution （the time limit to the measurement of zinc gluconate dissolution in zieold tables is 30 minates, limit of dissolution is 75%）