聚乙烯醇-透明质酸-胶原组织工程支架研究

以聚乙烯醇(PVA)、透明质酸(HA)和胶原蛋白(Col)为组分,构建组织工程三维多孔支架.将聚乙烯醇分别与不同质量的胶原和透明质酸复合,测定复合材料的含水率和膨胀率.扫描电镜观察材料横截面的表面形态.结果是不同分子质量的PVA与不同配比的Col和HA复合,得到的复合支架材料含水率为57.97%～81.26%,膨胀率为150.00%～459.20%.不同配比的复合支架材料具有不同的内部孔洞结构.结果表明,PVA-HA-Col复合支架材料具有较高的含水率和膨胀率,内部孔洞网络丰富,可作为组织工程支架材料.

Investigation of PVA-HA-collagen as scaffolds for tissue engineering

In order to investigate the feasibility of polyvinyl alcohol(PVA)-hyaluric acid(HA)-collagen(Col) as tissue engineering scaffold and to discuss the effect of PVA,HA and collagen on the structures and properties of this novel scaffold,PVA was blended with different amount of collagen and HA.The water content and swelling ratio of the scaffold were tested.SEM was used to observe the configuration of the inner section.The results show that scaffolds of different molecular weight of PVA compounded with differen...