肿瘤标志物研究进展

随着精准医疗的发展,肿瘤标志物越来越得到关注.综述了近期肿瘤标志物的突破性进展:肿瘤标志物研究内容逐步扩展,涉及基于肿瘤基因组和染色体变异、液体活检、表观遗传学和代谢组学等多方面的肿瘤标志物;肿瘤标志物相关检测技术飞速发展,包括液体活检、高通量基因测序、单细胞精准检测及其他新型技术等;并且随着这些新型高科技的不断发展,...

Advances in tumor markers

With the development of precision medicine, tumor markers have been paid more and more attention by researchers, and their understanding has gradually made a breakthrough. The research content of tumor markers has been gradually expanded to tumor markers based on tumor genome and chromosomal variations, liquid biopsy, epigenetics and metabolomics; moreover, tumor marker-related detection technologies have developed rapidly, including liquid biopsy, high-throughput gene sequencing, single-cell sequencing and other new technologies; furthermore, with the continuous development of these new high-technologies, tumor marker detection has achieved a breakthrough from single detection to multi-factor combined detection; finally, in clinical practice, tumor marker detection has played an important role in early tumor screening and diagnosis, guiding tumor treatment and predicting efficacy as well as predicting tumor recurrence, metastasis and prognosis, which is of great significance to improve the quality of cancer diagnosis and treatment, and fully realize precision medicine.