血小板分布宽度和血清白蛋白水平鉴别甲状腺肿瘤性质的临床进展

为观察和分析血小板分布宽度(PDW)、平均血小板体积(MPV)和血清白蛋白(Alb)水平对甲状腺癌与甲状腺良性结节的鉴别价值,选择2018年12月至2020年9月在安徽省阜阳市人民医院确诊的237例甲状腺癌患者作为研究组,并抽取在该院就诊的237例良性甲状腺结节患者作为对照组.观察2组患者PDW、MPV和Alb水平及预...

Differential value of platelet distribution width and serum albumin level between thyroid cancer and benign thyroid nodules

In order to analyze the differential values of platelet distribution width (PDW), mean platelet volumes (MPVs), and serum albumin (ALB) levels in thyroid cancer and benign thyroid nodules, 237 patients with thyroid cancer diagnosed in the hospital from Jan. 2016 to Sept. 2020 were selected as the study group, and 237 patients with benign thyroid nodules were selected as the control group. The PDWs, ALBs and MPVs of the two groups were observed and the clinical values of predicting thyroid cancer were evaluated. Results show that MPV and ALB of the study group are lower and PDW is higher than those of the control group, and the differences are statistically significant (P<0.05). PDW, MPV,ALB in the diagnosis of thyroid cancer AUC are not statistically significant (P > 0.05). The specificity of PDW, MPV and ALB is higher than that of PDW, MPV and ALB alone, and the sensitivity of PDW, MPV and ALB is higher than that of PDW, MPV and ALB alone. Therefore, PDW, MPV and ALB are of moderate clinical value in the differential diagnosis of benign and malignant thyroid nodules. Different combination of the three indexes is helpful to the diagnosis or exclusion of thyroid cancer.