| 桂参止痛合剂镇痛作用的实验研究 |
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| 引用本文： | 宋宏良,张崇烈,刘爱恒.桂参止痛合剂镇痛作用的实验研究[J].实验动物科学,2002,19(1):18-21. |
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| 作者姓名： | 宋宏良 张崇烈 刘爱恒 |
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| 作者单位： | 1. 天津市医药科学研究所,天津,300070
2. 天津市实验动物质量监测站,天津,300381 |
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| 摘 要： | 使用光热法、电刺激法、化学刺激法、模拟成痛经、牙痛、三叉神经痛等模型以观察桂参止痛合剂对各种疼痛的疗效。结果表明 ,桂参止痛合剂 5、10、2 0ml kg剂量组可使家兔对热辐射所致疼痛反应的阈值明显提高 ;对电刺激家兔齿髓所产生咀嚼运动和摆头反应有明显的抑制作用 ,可明显提高家兔对电刺激所致疼痛反应的阈值 ;可明显抑制K+所致大鼠三叉神经痛 ;可极明显地抑制缩宫素所致大鼠痛经扭体反应的次数及发生率 ;可极明显抑制前列腺素E1所致小鼠子宫痉挛扭体反应的次数。
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| 关 键 词： | 桂参止痛合剂 牙痛 三叉神经痛 痛经 |
| 文章编号： | 1006-6179(2002)01-0018-04 |
| 收稿时间： | 2002-03-25 |
| 修稿时间： | 2002年1月7日 |
The Study on Analgesic Effect of Sengui Mixture |
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| SONG Hong-liang\,ZHANG Chong-lie\,LIU Ai-heng\.The Study on Analgesic Effect of Sengui Mixture[J].Shiyan Dongwu Kexue,2002,19(1):18-21. |
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| Authors: | SONG Hong-liang\ ZHANG Chong-lie\ LIU Ai-heng\ |
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| Institution: | SONG Hong-liang\+1,ZHANG Chong-lie\+2,LIU Ai-heng\+1 |
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| Abstract: | The analgesic effect of Sengui mixture was confirmed by the methods of light-hot,electric stimulation and chemical stimulation.This experiment showed that after taking Sengui mixture (5\,10\,20ml/kg)orally,the liminal value of rabbit ache caused by calorediance was increase evidently;the response of rabbit's masticatory movement caused by electric stimulating tooth was inhibited;the tic douloureux caused by peniciline G K was calmed down;the uterine spasm caused by oxytocin and prostaglandin E1 was calmed also down. |
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| Keywords: | Sengui mixture Toothache Tic douloureux Painful menstruation |
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