A low molecular weight glycosaminoglycan from the human aorta |
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Authors: | R L Stevens J P Binette A Kimura R B Nimberg K Schmid |
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Institution: | (1) Department of Biochemistry, Boston University School of Medicine, Boston University Medical Center, 02118 Boston, Massachusetts, USA;(2) Present address: Department of Medicine, State University of New York, Buffalo;(3) Veterans Administration Hospital, 14215 Buffalo, N.Y., USA |
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Abstract: | Summary A low mol.wt, dialyzable glycosaminoglycan was isolated from human aorta and was found to be homogeneous on 2 dimensional electrophoresis. As judged by its electrophoretic mobilities and its hydrolysis by chondroitin sulfatase ABC, it was concluded that this hitherto unknown glycosaminoglycan is an oversulfated chondroitin sulfate.This study was supported by grants from the National Institutes of Health (GM-10374, HL-13262), U.S. Public Health Service. |
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