| Functional Imaging of Breast Tissue and Clinical Application |
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| 引用本文： | LI Kaiyang,LIU ShenglinSchool of Physics Science and Technology,Wuhan University,Wuhan 430072,Hubei,China. Functional Imaging of Breast Tissue and Clinical Application[J]. 武汉大学学报:自然科学英文版, 2006, 11(2): 373-376. DOI: 10.1007/BF02832125 |
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| 作者姓名： | LI Kaiyang LIU ShenglinSchool of Physics Science and Technology Wuhan University Wuhan 430072 Hubei China |
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| 作者单位： | LI Kaiyang，LIU ShenglinSchool of Physics Science and Technology，Wuhan University，Wuhan 430072，Hubei，China |
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| 基金项目： | SupportedbytheEnterpriseInnovationFoundationofWuhan(220,2004) |
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| 摘 要： | 0Introduction Near infrared(NIR)techniquesarebasedonsensitive,quantitativemeasurementsoffunctionalcontrastbe tweenhealthyanddiseasedtissue.Recently,researchersshowgreatinterestinmeasuringfunctionalpropertiesofbreasttis suesuchashemoglobinconcentrationoroxygensaturationbyNIRspectroscopyandNIRimaging[1,2].NIRlightcanpene trateseveralcentimetersintotissuebeforeitisattenuatedbe lowdetection.ThemainintrinsicmechanismsofNIRlightat tenuationintissuearethescatteringduetoindexofrefractionvariatio…
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| 收稿时间： | 2005-05-02 |
Functional imaging of breast tissue and clinical application |
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| Li Kaiyang,Liu Shenglin. Functional imaging of breast tissue and clinical application[J]. Wuhan University Journal of Natural Sciences, 2006, 11(2): 373-376. DOI: 10.1007/BF02832125 |
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| Authors: | Li Kaiyang Liu Shenglin |
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| Affiliation: | (1) School of Physics Science and Technology, Wuhan University, 430072 Wuhan, Hubei, China |
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| Abstract: | A novel approach to image hemoglobin concentration(ΔD hb) and oxygen saturation (ΔD oxy) of breast tissue is presented. The scenograph of dual-wavelength (760 and 850 nm) near infrared lights through breast tissue is acquired by high sensitive charge coupled device (CCD) camera. The evaluation criterion of the difference of ΔD hb and ΔD oxy between detected and referenced breast tissue can be obtained by a calculation formula without complicate caculation. This approach is applied to clinic detection in breast tissue. The ongoing clinical experiments indicate that malignant tumor usually exhibits characterize of “higher ΔD hb and lower ΔD oxy”, while benign lesion often shows “lower ΔD hb and higher ΔD oxy” or other characters. So it is useful to assist the diagnosis of breast disease. Foundation item: Supported by the Enterprise Innovation Foundation of Wuhan (2-2-0, 2004) Biography: LI Kaiyang(1963-), male, Associate professor, research direction, biomedical physics and biomedical engineering. |
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| Keywords: | near-infrared hemoglobin concentration oxygen saturation functional imaging breast tumor |
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