Elevation of serum xanthine oxidase following halothane anesthesia in the rat |
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Authors: | Sh. Giler E. Ventura E. Levy I. Urca O. Sperling A. de Vries |
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Affiliation: | (1) Department of Surgery B, Department of Anesthesiology, Tel-Aviv, University Medical School, Beilinson Medical Center, Petah Tikva, Israel;(2) Rogoff-Wellcome Medical Research Institute, Tel-Aviv, University Medical School, Beilinson Medical Center, Petah Tikva, Israel |
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Abstract: | Summary Halothane anesthesia was found to be hepatotoxic in the rat, as demonstrated by a significant elevation of serum xanthine oxidase (SXO) level. SXO appeared to be a more sensitive marker of liver damage than serum, glutamic oxalacetic transaminsa. SXO was found to be elevated also following exposure to relative hypoxia. |
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