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Regression of genetically determined polycystic kidney disease in murine organ culture |
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| Authors: | E D Avner W E Sweeney N P Piesco D Ellis |
| Abstract: | Cystic kidneys from the mutant CPK strain of C57BL/6J mice were cultured in serum-free organ culture. During 120 h of incubation in chemically-defined medium, CPK cystic tubular changes underwent complete regression. Environmental factors regulate the expression of genetically determined polycystic kidney disease in this model. |
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