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Uptake of D-glucose anomers by rat retina
Authors:J Okuda  I Miwa  M Sato  T Murata
Institution:(1) Department of Clinical Biochemistry, Faculty of Pharmacy, Meijomacr University, Tempaku-ku, 468 Nagoya, (Japan);(2) Present address: Department of Biopharmacy, Shizuoka College of Pharmacy, Oshika, Shizuoka, (Japan)
Abstract:Summary Uptake ofd-glucose anomers by isolated rat retina was studied. After 3 min incubation at 37°C in the presence of agr or beta anomer (750 mgrg/ml), a significantly greater uptake (1.32 mg/g wet tissue) of beta-anomer was observed compared with that of agr-d-glucose (1.11 mg/g wet tissue). This result and other data suggest that the carrier ford-glucose transport in the retina prefers the beta-anomer stereospecifically.Acknowledgment. The authors are grateful to Mr S. Suzuki for his technical assistance.
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