Uptake of D-glucose anomers by rat retina |
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Authors: | J Okuda I Miwa M Sato T Murata |
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Institution: | (1) Department of Clinical Biochemistry, Faculty of Pharmacy, Meij University, Tempaku-ku, 468 Nagoya, (Japan);(2) Present address: Department of Biopharmacy, Shizuoka College of Pharmacy, Oshika, Shizuoka, (Japan) |
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Abstract: | Summary Uptake ofd-glucose anomers by isolated rat retina was studied. After 3 min incubation at 37°C in the presence of or anomer (750 g/ml), a significantly greater uptake (1.32 mg/g wet tissue) of -anomer was observed compared with that of -d-glucose (1.11 mg/g wet tissue). This result and other data suggest that the carrier ford-glucose transport in the retina prefers the -anomer stereospecifically.Acknowledgment. The authors are grateful to Mr S. Suzuki for his technical assistance. |
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