| 奥沙普秦的线性扫描极谱法测定 |
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| 引用本文： | 拓宏桂,项小燕,张著森. 奥沙普秦的线性扫描极谱法测定[J]. 龙岩学院学报, 2011, 29(5): 24-26 |
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| 作者姓名： | 拓宏桂 项小燕 张著森 |
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| 作者单位： | 龙岩学院化学与材料学院,福建龙岩,364012 |
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| 摘 要： | 用线性扫描极谱法和循环伏安法研究奥沙普秦在0.05mol.L-1HAc-NaAc缓冲溶液(pH5.18)中的电化学行为。奥沙普秦于-1.221V(vs.SCE)处产生一灵敏的吸附波,奥沙普秦浓度在4.0μg.L-1～2000.0μg.L-1范围时,其一次微分线性扫描峰电流与奥沙普秦浓度呈良好的线性关系,相关系数r=0.99920(n=15),检出限为2.4μg.L-1。对200.0μg.L-1奥沙普秦溶液进行6次平行试验,RSD为1.02%,回收率在94.3%～96.2%之间,方法可用于其在片剂中含量的测定。
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| 关 键 词： | 药物分析 奥沙普秦 线性扫描极谱法 吸附波 |
Linear Scanning Polarographic Determination of Oxaprozin |
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| TA Hong-gui,XIANG Xiao-yan,ZHANG Zhu-sen. Linear Scanning Polarographic Determination of Oxaprozin[J]. Journal of Longyan Univercity, 2011, 29(5): 24-26 |
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| Authors: | TA Hong-gui XIANG Xiao-yan ZHANG Zhu-sen |
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| Affiliation: | TA Hong-gui,XIANG Xiao-yan,ZHANG Zhu-sen |
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| Abstract: | The electrochemical behavior of Oxaprozin was studied by linear scanning polarographic and cyclic voltammograms method.In an acetate buffer solution of pH 5.18,a sensitive reductive wave of Oxaprozin appeared at 1.221V（vs.SCE）.The linear relationship between the peak current and the Oxaprozin concentration in the range of 4.0μg·L-1～2000.0μg·L-1（r=0.9992,n=15） was observed.The detection limit of the method was 2.8μg.L-1.RSD obtained from the data of 6 independent determinations at the concentration level of 200.0μg.L-1 was 1.02%,Recoveries obtained were in the range of 94.3%～96.2%.This method can be applied to the determination of Oxaprozin in tablets. |
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| Keywords: | pharmaceutical analysis Oxaprozin scanning polarographic adsorptive wave |
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