阿特拉津分子印迹聚合物微球的制备及表征

以阿特拉津（Atrazine）为模板分子,甲基丙烯酸（MAA）为功能单体,乙二醇二甲基丙烯酸酯（EDMA）为交联剂,采用沉淀聚合法制备了粒径约210nm的阿特拉津纳米分子印迹聚合物（MIPs）微球.采用紫外分光光度法确定了模板分子与功能单体的最佳物质的量比为1:4.Scatchard分析表明,分子印迹聚合物纳米微球存在两种不同的结合位点,最大表观吸附量(Q_max)和平衡离解常数（K_d）分别为Q_max1=38.08μg/g,K_d1=0.2489μg/L,Q_max2=310.33μg/g,K_d2=6.6269μg/L.此方法制备的分子印迹聚合物对阿特拉津具有良好的选择性吸附能力.

Preparation and characterization of Atrazine molecularly imprinted polymer microspheres

Molecularly imprinted polymer（MIPs） nano-microspheres with a uniform particle size of 210 nm were prepared by using precipitation polymerization of methacrylic acid（MAA） as the functional monomer,ethylene glycol dimethacrylate（EDMA） as the crosslinking agent,azodiisobutyronitrile（AIBN） as the initiating agent and Atrazine as the template in acetonitrile.UV spectrometry was employed to demonstrate the mechanism of the interaction between Atrazine and MAA.It showed that the optimal proportion of Atrazine-MAA complexes was 1:4（mol ratio）.Analysis of the Scatchard plot revealed that there were two kinds of binding sites in MIPs and their apparent maximum binding capacity(Q_max) and dissociation contents（K_d） were Q_{max 1} = 38.08μg/g, K_d1 = 0.248 9μg/L for high affinity binding sites and Q_{max 2} = 310.33μg/g,K_d2 = 6.626 9μg/L for low affinity binding sites respectively.The molecularly imprinted polymers synthesized with this method exhibited a good selective adsorption capacity for Atrazine.