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Effect of aloe lectin on deoxyribonucleic acid synthesis in baby hamster kidney cells |
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| Authors: | A Yagi K Machii H Nishimura T Shida I Nishioka |
| Institution: | (1) Faculty of Pharmacy and Pharmaceutical Sciences, Fukuyama University, 729-02 Fukuyama, Hiroshima, (Japan);(2) Oyodo Research Laboratories, Maruho Co., Ltd, 531 Osaka, (Japan);(3) Clinical Research Center for Reumato-Allergology, National Sagamihara Hospital, 228 Sagamihara, Kanagawa, (Japan);(4) Faculty of Pharmaceutical Sciences, Kyushu University, 812 Fukuoka, (Japan) |
| Abstract: | Summary A homogeneous glycoprotein (mol.wt 40,000) containing 34% carbohydrate was isolated fromAloe arborescens var.natalensis. At a concentration of 5  g/ml, this glycoprotein was shown to stimulate deoxyribonucleic acid (DNA) synthesis in baby hamster kidney (BHK) cells and to have the properties of a lectin which reacts with sheep blood cells. The chemical and physical properties of the glycoprotein (aloe lectin) are also discussed. |
| Keywords: | Aloe arborescent varnatalensis glycoprotein aloe lectin deoxyribonucleic acid synthesis baby hamster kidney cells |
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