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Liver function during chronic renal failure in rabbits
Authors:E Tvedegaard  H E Poulsen  H Vilstrup  H K Thomsen
Institution:(1) Medical Department P Rigshospitalet and Institute of Pathology, Hvidovre Hospital, Blegdamsvej 9, DK-2100 Copenhagen, (Denmark);(2) Medical Department A, Rigshospitalet and Institute of Pathology, Hvidovre Hospital, Copenhagen, (Denmark)
Abstract:Summary In rabbits with chronic renal insufficiency the prothrombin index was increased by 25% and the alanine aminotransferase activity decreased by 20%; the results of other routine tests of hepatic function were not affected. The galactose elimination capacity was decreased by 12%, whereas the body clearance of antipyrine was unchanged. No change in hepatocytic structure was found.
Keywords:Rabbits  renal failure  chronic  liver function  prothrombin index
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