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Purealidin A,a new cytotoxic bromotyrosine-derived alkaloid from the Okinawan marine spongePsammaplysilla purea
Authors:M. Ishibashi  M. Tsuda  Y. Ohizumi  T. Sasaki  J. Kobayashi
Affiliation:(1) Faculty of Pharmaceutical Sciences, Hokkaido University, 060 Sapporo, (Japan);(2) Pharmaceutical Institute, Tohoku University, 980 Sendai, (Japan);(3) Cancer Research Institute, Kanazawa University, 920 Kanazawa, (Japan)
Abstract:Summary A new bromotyrosine-derived alkaloid with antileukemic activity, purealidin A (5), has been isolated from the Okinawan marine spongePsammaplysilla purea and its chemical structure elucidated on the basis of the spectroscopic data.
Keywords:Antileukemic activity  purealidin A  bromotyrosine-derived alkaloid  sponge  Psammaplysilla purea
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