| 镉对中国林蛙外周血细胞微核及核异常的诱导效应 |
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| 引用本文： | 王维君,张育辉.镉对中国林蛙外周血细胞微核及核异常的诱导效应[J].陕西师范大学学报,2005,33(4):95-98. |
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| 作者姓名： | 王维君 张育辉 |
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| 作者单位： | 陕西师范大学生命科学学院,陕西西安710062 |
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| 基金项目： | 陕西省自然科学基金资助项目(2001SM26) |
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| 摘 要： | 用不同剂量Cd2^＋注射林蛙，5d后取血制片，光镜观察，探讨了不同剂量Cd2^＋对中国林蛙红细胞形成微核及核异常的影响．结果表明，Cd2^＋可诱导红细胞产生微核和核异常．Cd2^＋剂量高于0．2mg／kg作用5d后，对林蛙血细胞具有明显的毒性效应．Cd2^＋剂量低于0．5mg／kg范围内，微核与核异常细胞率随Cd2^＋的增加呈上升趋势；当Cd2^＋剂量高于0．5mg／kg时，微核与核异常细胞率随Cd2^＋的增加而下降．
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| 关 键 词： | 镉 中国林蛙 红细胞 微核 核异常 |
| 文章编号： | 1672-4291(2005)04-0095-04 |
| 修稿时间： | 2005年5月20日 |
Inductive effects of cadmium chloride on micronuclei and nuclear anomalies in erythrocytes of Rana chensinensis |
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| WANG Wei-jun,ZHANG Yu-hui.Inductive effects of cadmium chloride on micronuclei and nuclear anomalies in erythrocytes of Rana chensinensis[J].Journal of Shaanxi Normal University: Nat Sci Ed,2005,33(4):95-98. |
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| Authors: | WANG Wei-jun ZHANG Yu-hui |
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| Abstract: | In order to investigate the effects of Cd~(2 ) on the micronuclei(MN) and other nuclear anomalies(ONA) in erythrocytes of peripheral blood of Rana chensinensis.Frogs are injected with different dosage Cd~(2 ) for 5 d,making blood slides and observing with microscope.The results indicate that Cd~(2 ) could induce the appearance of MN and ONA distinctly.When the dose oversteps 0.2 mg Cd~(2 )/kg,Cd~(2 ) could cause significant genetic damages to the peripheral blood cells of R.chensinensis.Within a dose range of 0.5 mg Cd~(2 )/kg,the frequencies of MN and ONA show a dosage-dependent increase.However,it decreases with the dose over 0.5 mg Cd~(2 )/kg. |
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| Keywords: | cadmium Rana chensinensis erythrocyte micronucleus nuclear anomaly |
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