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中药复方制剂抗鸡新城疫病毒活性的研究
引用本文:索化夷,蒋德阳,汤承,刘群. 中药复方制剂抗鸡新城疫病毒活性的研究[J]. 西南民族学院学报(自然科学版), 2007, 33(2): 316-318
作者姓名:索化夷  蒋德阳  汤承  刘群
作者单位:西南大学食品学院 重庆400716(索化夷),成都市农业委员会畜牧兽医处 成都610041(蒋德阳),西南民族大学生命科学与技术学院 成都610041(汤承,刘群)
摘    要:病毒病严重危害养殖业的发展,从传统中药筛选有效抗病毒药物是抗病毒研究的重要内容之一.本试验以鸡新城疫病毒(NDV)为模式病毒,评价了一种水萃取浓缩制备成的中药复方颗粒剂的抗病毒活性.通过鸡胚保护试验、人工攻毒保护试验、对自然病例的治疗试验等证实,该制剂具明显地抗鸡新城疫病毒的活性.该制剂0.13mg/胚即可保护50%鸡胚抵抗NDV强毒的致死作用;按0.5g/kg体重口服,人工感染病例的对照组存活率提高54%;对实时荧光定量PCR确诊的ND病鸡4500只进行治疗,0.5g/kg体重饮水,连续使用5天,用药后第2天症状明显减轻,3天后可基本控制死亡,治愈率为95%.

关 键 词:中药  复方制剂  鸡新城疫
文章编号:1003-2843(2007)02-0316-03
修稿时间:2006-12-11

Study on the effect of anti-NDV with Chinese traditional compound medicine
SUO Hua-yi,JIANG De-yang,TANG Cheng,LIU Qun. Study on the effect of anti-NDV with Chinese traditional compound medicine[J]. Journal of Southwest Nationalities College(Natural Science Edition), 2007, 33(2): 316-318
Authors:SUO Hua-yi  JIANG De-yang  TANG Cheng  LIU Qun
Affiliation:1. School of Food Science, Southwest University, Chongqing 610041; P. R. C. 2. Department of Animal Husbandry and Veterinary ,Chengdu Agricultural Commission, Chengdu 610041, E R. C.; 3. School of Life Science and Technology, Southwest University for Nationalities, Chengdu 610041, E R. C.
Abstract:The effect of anti-NDV with Chinese traditional compound medicine (CTCM) is evaluated in this test. The results show that dosage of 0.13mg CTCM /embryo can protect 50% embryo from lethal attacking by NDV. The livability of experimental infectious chicken treated with dosage of 0.5g CTCM/kg body weight orally is 54% higher comparing with control. A herd of 4500 chickens suffering from ND diagnosed by real-time PCR is treated with dosage of 0.5g CTCM/kg body weight orally continuous 5d. The symptom of ND is catabolic markedly 2d and death can be controlled 3d post-treatment. Curing rate reaches 95%, which is better than control.
Keywords:Chinese traditional medicine  compound preparation  NDV  
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