Relationship between polyamine accumulation and RNA biosynthesis and content during the cell cycle |
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| Authors: | M. H. Goyns |
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| Affiliation: | (1) Department of Zoology, University of Cambridge, CB2 3EL Cambridge, UK;(2) Present address: Department of Histology and Cell Biology (Medical), University of Liverpool, P. O. Box 147, L69 3BX Liverpool, UK |
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| Abstract: | Summary Polyamine accumulation was related to RNA biosynthesis and content during the cell cycle of CHO-K1 and HeLa cells. The highest correlations were observed between polyamine accumulation and RNA content. Feeding, serumstarved cultures of embryonic chick fibroblasts, which exhibit a 3-fold increase in RNA content, demonstrated that RNA content was most closely paralleled by spermidine content.I acknowledge the receipt of a Medical Research Council studentship. |
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