New lectin receptors in carcinoembryonic antigen (CEA) |
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Authors: | G Wintzer G Uhlenbruck G Steinhausen H Carmann |
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Institution: | (1) Chirurgische und 1. Medizinische Universitätsklinik, D-5 Köln 41, Federal Republic, of Germany;(2) Immunological Laboratory, F. Hoffmann-La Roche & Co AG, CH-4133 Schweizerhalle, Switzerland |
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Abstract: | Summary The glycoprotein CEA (carcinoembryonic antigen) carries carbohydrate groups, which react with the plant lectins fromAgaricus bisporus, Arachis hypogaea (peanut), with Tridacnin from invertebrate clams and with the anti-A lectins from snails. Accordingly, it has cryptantigenic structures, which correspond to the T or T-like antigen, the Tridacnin receptor and to the so called A-like antigen.Acknowledgment. This work has been supported by Landesamt für Forschung NRW. |
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