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| 有机化学与生命科学的碰撞——2016年生物有机化学热点回眸 | |
| 引用本文： | 郑庆飞,王守锋.有机化学与生命科学的碰撞——2016年生物有机化学热点回眸[J].科技导报(北京),2017,35(1):21-29. |
| 作者姓名： | 郑庆飞 王守锋 |
| 作者单位： | 1. 中国科学院上海有机化学研究所, 生命有机化学国家重点实验室, 上海 200032; 2. 济南大学化学化工学院, 山东省氟化学化工材料重点实验室, 济南 250022 |
| 摘 要： | 生物有机化学旨在阐明复杂生命体系中的内在化学机制，以及通过理性的设计和改良来创造能够由于有机合成化学的生物大分子催化剂。本文遴选2016年发表于《Science》《Nature》《PNAS》《Nature Chemistry》等期刊的部分重要研究结果，回顾2016年生物有机化学领域取得的突破性进展。 |
| 关 键 词： | 生物有机化学 化学生物学 定向进化 人工酶 生物催化 |
| 收稿时间： | 2016-12-25 |
When organic chemistry meets biological science: Recent advances in bio-organic chemistry in 2016 |
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| ZHENG Qingfei,WANG Shoufeng.When organic chemistry meets biological science: Recent advances in bio-organic chemistry in 2016[J].Science & Technology Review,2017,35(1):21-29. | |
| Authors: | ZHENG Qingfei WANG Shoufeng |
| Institution: | 1. State Key Laboratory of Bioorganic and Natural Products Chemistry;Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, China; 2. Shandong Provincial Key Laboratory of Fluorine Chemistry and Chemical Materials;School of Chemistry and Chemical Engineering, University of Jinan, Ji'nan 250022, China |
| Abstract: | The investigation of bio-organic chemistry focuses on elucidation of the mechanisms involved in complex biological systems, as well as the design and optimization of efficient biomacromolecule-based catalysts for organic synthesis. In this paper, we select several representative papers published on Science, Nature, PNAS, Nature Chemistry, etc. to summarize the most important progress in this research field. |
| Keywords: | bio-organic chemistry chemical biology directed evolution artificial enzyme biocatalysis |
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