超声波辅助催化合成尼泊金正辛酯

在超声波辐射下以对羟基苯甲酸和正辛醇为原料、SnCl4为催化剂合成尼泊金正辛酯.考察了原料配比、催化剂用量、超声波辐射功率及辐射时间对尼泊金正辛酯收率的影响.结果表明:超声波辐射下SnCl4具有良好的催化活性.最佳工艺条件为:对羟基苯甲酸13.8 g(0.1 mol),醇酸物质的量比2.5:1,环己烷15 mL,催化剂0.7 g,300 W超声波辐射30 min,尼泊金正辛酯收率达到90%以上.

Catalytic Synthesis of Octyl Nipagin by Ultrasonic Assisted Method

The octyl nipagin is synthesized by ultrasonic assisted method with p-hydroxy benzoic acid and n-caprylic alcohol as the raw material and SnC14 as catalyst. Effects of molar ratios of the reactants, catalyst dosage, and ultrasonic wave power, radiation time on the yield of octyl nipagin are investigated. Results show that the catalytic SnC14 has good catalytic activity under ultrasonic. Under the optimal conditions of p-hydroxy benzoic 13.8 g （0.1 mol）, mole ratio of n-caprylic alconol to p-hydroxy benzoic acid 2.5 ： 1, cyclohexane 15 mL, catalyst 0.7 g and 30 rain radiation with ultrasonic wave power of 300 W, the yield of octyl nipagin reaches 90%.