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老年非心源性胸痛与酸反流的临床探讨
引用本文:袁爱梅,梁兴伦,朱敏洁. 老年非心源性胸痛与酸反流的临床探讨[J]. 科技资讯, 2008, 0(2)
作者姓名:袁爱梅  梁兴伦  朱敏洁
作者单位:上海市杨浦区中心医院干部保健科
摘    要:目的通过对老年非心源性胸痛(NCCP)与酸反流关系的了解,探讨质子泵抑制剂(PPI)试验对NCCP病因诊断价值.方法对42例老年NCCP患者进行胃镜、24小时食管pH监测、质子泵抑制剂(PPI)试验性抗反流治疗.结果42例老年NCCP中,有20例(47.62%)的Deme吼日r总积分>14.72;有14倒(53.55%)霄镜检查诊为反流性食管炎;有29例(69.05%)PPI试验Fe,I生。阳性卒明显高于与霄镜检生、24小时食管pH监测,有显著差异(P<0.05);PPI试验敏感性为90%,PPI试验特异性为81.82%.结论NCCP主要原因是酸反流,PPI试验可作为老年NCCP患者简便、经济、有效的病因诊断方法.

关 键 词:非心源性胸痛  胃食管反流  质子泵抑制剂

To investigate the relationship between noncardiac chest pain and acid reflux in the aged
Yuan Aimei Liang Xinglun Zhu Minjie. To investigate the relationship between noncardiac chest pain and acid reflux in the aged[J]. Science & Technology Information, 2008, 0(2)
Authors:Yuan Aimei Liang Xinglun Zhu Minjie
Affiliation:Yuan Aimei Liang Xinglun Zhu Minjie (Department of Geriatrics; Yangpu central hospital Affiliated to Shanghai Jiaotong University; Shanghai 200090; China);
Abstract:Objective To probe the relationship of non-cardiac chest pain and acid reflux in the aged and test the efficacy of proton pump inhibitors(PPI)as a diagnostic test in the evaluation of NCCP.Methods 42 patients,who presented with recurrent chest pain complaints of a noncardiac etiology,were using high-dose omeprazole(40 mg/d orally twice daily)for 28 days.Findings were compared with those of endoscopy and ambulatory 24-hour esophageal pH monitoring.Patients were instructed to record all chest pain episodes be...
Keywords:non-cardiac chest pain  gastroesophageal reflux  proton pump inhibitors
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