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The dose-dependence of sister chromatid exchanges induced by 3 hydrocarbons,in the in vivo bone marrow test with Chinese Hamsters
Authors:U Bayer  T Bauknecht
Institution:(1) Forstbotanisches Institut der Universität, Bertoldstrasse 17, D-7800 Freiburg im Breisgau;(2) Institut für Humangenetik und Anthropologie der Universität, Albertstrasse 11, D-7800 Freiburg im Breisgau, Federal Republic of Germany, BRD
Abstract:Summary In accordance with their carcinogenic effects, 7, 12-dimethylbenzanthracene and 3,4-benzo(a)pyrene induce sister chromatid exchanges in the bone marrow of Chinese Hamsters in vivo. Phenanthrene is inactive. A dose dependence of induced sister-chromatid exchanges can be shown.Work carried out under Contract No. 022-74-1-ENVD of the E. G. Environmental Research Programme and the Bundesministerium für Forschung und Technologie (Nr. MT 420).
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